And as soon as you get like a hundred patients per uh physician cap, that's when it really becomes this sort of like hardcore commercial enterprise just because people are always trying to push the edge. I do think that that treatment and and rehabilitation should be available to them even if they are pushing the boundaries. And this is the difference between heroin use and heroin dependence/addiction. But there is a whole lot of action and historical building that goes into creating the systems in which these drugs now exist. So what it allowed for was simply the acceptance of open air drug use with no no remediation or uh or responsibilities whatsoever. We haven't done anything when we've had over 100,000 overdose deaths per year. Very few people understand that these three drugs. [music] [music] [music] Welcome. I'm uh here and honored to be with Emily Duftton. Uh she's a PhD in urban studies perhaps. Uh she'll maybe rectify that uh uh term, but she's a historian. She's the author of a few a couple books on addiction. Uh most recently, Addiction, Inc. uh Inc. period um as in incorporated and it came out University of Chicago I believe April of this year and it's an interesting read um she goes over the history of methadone and um I suppose maintenance therapy um principally concentrated in the 60s7s and beyond and um it has policy implications for today for uh narcotic and drug treatment um I thank you so much for being on Emily u what did I get wrong first of all and uh tell what [laughter] what what inspired you to to write this book? Oh, well, thank you so much for having me. I'm really happy to be here. Um, my PhD is actually in American studies, which is uh sort of a nebulous field of study. Uh, but for the most part, I focused on American history and cultural uh cultural history specifically. Um, I was inspired to write this book because I grew up in Allentown, Pennsylvania, which was very hard hit by the prescription opioid epidemic in the early 2000s. uh and a very good friend of mine passed away. He committed suicide by hanging himself um from a tree in the woods behind our old middle school after about 15 years of steady and escalating and increasingly chaotic opioid use. He was only using pills. He never injected heroin. He never joined in his roommate's use of meth, but he was very much a person who became extremely dependent on prescription opioids. And when he passed away, I was very uh upset by his death because he was a good buddy of mine and I really enjoyed his company. Uh and I was very confused by it because I thought he was one of the most vivacious person uh people I'd ever met in my entire life. And to lose him when he was just 30 years old was very disturbing. But of course, it wasn't just him that we lost. There was actually a number of people from my old high school whom we had lost to either um overdoses, opioid overdoses or uh suicides for a number of years to the point where you would go to a reunion and they were just getting smaller and smaller because our population was just being cut down. And I was really upset by this because it was a small high school. We were all very close and I was losing all of these colleagues and friends of mine. And so I had just published my first book which was about the history of cannabis activism for and against legalization from the 1960s to today. And I was kind of fishing around for another topic to write about. And I realized my friend Dana's death posed um kind of a research problem that I could start to maybe potentially write a book proposal for. So I started asking a lot of the doctors and researchers and experts whom I had come to know through my years of working in drug history um what they would have done if my friend Dana had presented for treatment. And this was back in the long ago days of 2018. And every single one of them unanimously said he should have been placed on medicationass assisted treatment which was the term for uh this protocol at the time. I know it's moved on to mode or mood medications for opioid use disorder, but uh I continue to use medication assisted treatment just because it was the term that was used by the federal government, scientists, researchers, doctors, and patients at the time. And I still think it's actually like a really good sort of all-encompassing treatment uh term. Um but they said he should have been placed on Matt, MAT, medication assisted treatment. And I asked what that was. I mean, I was familiar with some of it, but I wasn't deeply familiar with it. And they explained it was the use of one of three FDA approved drugs either methadone, nalrexone or bupinorphine uh in con combination with various other services to allow a person to move away from street or elicit or chaotic drug use into a form of recovery. And I was like, well, you know, sounds great, right? I'm coming at it from I have no medical background whatsoever. As I was saying to you before, the sight of blood makes me incredibly queasy. Um, but I was intrigued by this. I was like, well, what are these three FDA approved drugs? Why aren't they so well supported by the number of people I'm talking to? And of course, why didn't Dana get them or the number of other people who had died from my high school? Why didn't they get them? And that launched me on an 8-year process to dig up the history of these drugs, where they came from, who developed them, and why. and of course why they are not necessarily uh a strong or a sufficient enough response to our larger opioid epidemic today. And that's kind of what brings us up to and you're right, my book was released in April, April 13th of this year from the University of Chicago Press. So that's that's that brings you up to today [laughter] or six months ago at least when the book came out. Congratulations. I assume you've done the book too and interviews and so forth. uh what what's the uh this is not to just save myself time but what what's the question that challenges the most or you find most memorable what's the point that you want to bring to bear on on the public um for their knowledge and and where do you think their lacuna absence of of expression and knowledge on this topic is or are I think the biggest lacuna is that we very few people understand that these three drugs all three of them and including actually a fourth drug that was also developed under the umbrella of medication assisted treatment but we no longer use it today. They were all developed as a very radical public health program in the 1970s which over the past 50ome years has transformed into extraordinarily privatized profitering uh sort of commercial um expedition today. And that is not necessarily functional for actually treating the opioid epidemic in the United States. And it's too bad that we lost this public health uh sort of commitment to it. And I think we blame the wrong people and we don't fully understand the history. And that is sort of the I mean that's sort of the driving the the the driving uh force behind what I what I wrote. Um and why I'm trying to bring this history back into the public light. Yeah. You know the seven blind men and the elephant. You know that parable. Mhm. Sure. Yeah. I mean I you and I come at this a little bit differently. I'm not going to I'm going to kind of suppress my my natural urges um [laughter] for a little bit, but you know, I um um you know, I'm aware of the MIAT aspects and and the drugs that are in in use. Um I I'm not sure I agree with your conclusion, but this is kind of would be at the end of this interview, but um while we're on this topic, um you you the way I see it, the way I interpret your book is that um the kind of fall from grace was taking this MAT, this kind of at the time was methodone treatment. There were there were other things as well. was the LAM and and and Nrexen, but principally methadone for decades until bupinorphine came about um 2000s. Um but you see kind of the uh the fall from from grace as the privatization of methadone clinics. Is that right? I have that right? And and and similar along those lines, just to extend the question slightly, I apologize. um it would be that you would see the the model um being more uh state controlled and or federal controlled um to take the profit motive out of the methodone clinics. And so my my ancillary question on top of whatever you want to discuss about that would be how would that improve things? Well, I don't know if it necessarily would at the point at this point, right? I think is it's a little bit too complicated but I mean other countries are completely sufficient at providing a level of care whether it comes with MAT or not for opioid use disorder or any other form of substance use disorder that doesn't necessarily exploit patients and treat them simply as customers in a system to be uh you know to be sorted profited off of and I don't know if that necessarily needs to be federally controlled. The United States is obviously a far larger country than places like Switzerland or Portugal that do have systems like this in place. But I think on a state-by-state basis, you can make this stuff available in a non-commercial way. I spent a lot of time in St. Louis, Missouri, uh at the u at the um clinics that are run through ARCA, the assisted recovery centers of America through Percy Menses, who I know you know as well and you interviewed. Um he works very closely with the state government. He works very closely with a lot of other partners to provide resources to individuals who are seeking help. And he does not exploit these people. He doesn't make uh he doesn't make these programs available in a way where like you're charging every single day when if someone walks in the door. These are a wide variety of sources that include medication, but he mostly focuses on buprenorphine and nrexone, which is of course an opioid antagonist, so you're not necessarily on maintenance for the rest of your life. He also provides things like food, housing, job placement. Um, there's a wide variety of resources that are available to people in St. Louis and beyond through ARCA that I think are a model that other states could follow. The nationalized system that was founded in the US in 1971 is an extraordinary moment in American history, but I don't know if it's necessarily something that we could recreate now. I think there was like this moment and there were a whole lot of factors driving what Nixon was doing when he instituted this model, but I don't know if that's necessarily true anymore. We don't have the same models. We haven't done anything when we've had over 100,000 overdose deaths per year. Um, but I do think on the state level, especially with money that's coming through either the opioid settlement funds or through the state uh state uh uh federal funds that go through the states, there's a lot of options and opportunities to make treatment available to individuals outside of commercial entities that I think would be valuable to pursue. Yeah. So, um there's a lot there to parse. Uh hopefully we'll come back to to any or all of it. Um you did mention the settlement. So this is interesting to me. Um, I wrote an article on uh Purdue Pharma and I I'm not a you know, as a as a physician um you know before I I I wound up treating people with buprenorphine in the 2000s but before that I was uh um alive and well and and treating patients from the 1980s on and I had my own place in River Massachusetts 1987 on it's like a primary care office walk and whatever and so I had my regular codery of patients but I would have um kind of a little bit don't don't misinterpret this anybody, but you know, if you have a bright light out there in the in the summer, they're moths. Now, you may not want them, but they're attracted to the light. Now, there's a great great Norm Coleman joke about this. Uh, I recommend people look it up. It's with Conan and Brian. It's one of the great jokes of all time. Anyway, um, and so having a a clinic like that, a storefront clinic with walk-in aspects, uh, I attracted a lot of people looking for drugs. uh poly we call they call it poly pharmacy but really it's also poly doctoring um because they have uh frankly the opposite of lack of access they have complete access they have you know at the time it's called Medicaid cards then became mass health cards Massachusetts but it's basically they have you know formal welfare benefits um and they have cart blanch um to to see physicians and they would do that over and over again they would um kind of like um you know on the merry ground they collect the rings if that's still a thing um or Pokemon, collect them all or whatever. So they they would go from doctor to doctor and they would kind of stop at me and uh I actually heard later on that my term in their group was Dr. No, the James Bond villain, right? I kind of think of myself as Dr. No at all, but but they they just had Dr. No because I would say no because I had this thing where I while they were, you know, signing in, whatever, you know, it was kind of like there were things about them that kind of rang a bell for me. you know, they'd come from another town, they had pain that wouldn't be solved by just low-level percoet. They needed, you know, uh, higher level oxycontton and so forth. Anyway, um, but I would call smarteries and see that they had had prescriptions yesterday, for instance, for right 90 of X and 30 of Y the day before and what and it was kind of before computers a lot of this stuff. I mean, not quite, but before the the integration so anyway. Um but so that that's kind of a little of a background of stuff I do. But um you know and these people were these people were seeking um or various other pain addiction treatment. They would want Oxycontton or or something of that level. They wanted some higher dose um you know prescription narcotic um and they liked Oxycontton but it was Oxycontton anyway. So I'm I'm doing two things some from opioid painkiller but not like a not like a treatment drug. They're looking for specifically like a painkiller. Yeah. Well, yeah. And mind you, I think a lot of them were selling to be honest with you. They they were collecting and selling. So, they were scavenging. You know, I actually call it raccooning. It's my own term. I don't know if anybody else used it. Um, you know, raccoons are are reasonable animals out in the wild, but, you know, in the urban environment, they're they're they're tipping over garbage cans and hunting for what they can. This is kind of the raccooning aspect where you're collecting stuff. Um, anyway. Um, but so so that's kind of my own interaction with continent in the day. Um, but more recently, you know, I I re I re because Purdue paid out this huge settlement. Um, and I researched it and and and to be honest with you, I kind of feel like Purdue was scapegoed. Um, Oh, yeah. A bit. They were and they're not paying as much as they could. And there but there's lots of other people who are paying the money, too. Well, yeah, but but they went my only point there's a long roundabout. I apologize, but I think, you know, like Willie Sutton, you know, why did you rob banks? Because that's where the money is. uh they went after Purdue Frederick uh at the time or Purdue Pharma because they had been bestin-class. They were making kind of the boutique version of these narcotic pills and and their pills frankly were not the ones people were injecting and so forth. That didn't that wasn't really the basis of the injectable um crisis. You know, people were smooshing their their other narcotics and snorting all kinds of stuff. Um and they actually made an abuse deterrent formula. And I think they their actual component of the number of pills that people were overdosing on was was minuscule. was never like never bounded beyond like 3 to 4% of the total. So I think there are other characters but they were generic and they weren't making the profit margin anyway. So that that's a little bit of a preface a little bit about me and so forth but I apologize about that. But in Diviar, which is a a um a I guess a a submerger of Wreckit was wrecked Coleman originally. Then they made Buponorphine um as a as a um an analesic pain medication like a narcotic and then it became Wreckit Benkeeser. They they merged with like Swiss company or something like that. Dutch Yeah, it was a Dutch. Dutch. Thank you. Sorry about that. Um but you know in a in a sense it's exactly almost the same paradigm or parable of the Purdue aspect which is they did exactly what the government wanted. Purdue was asked to make an abuse deterrent formula. They did they made the perfect one oxycontton one I call it. Then they actually a few years later made Oxycontton what I call oxycontton 2 which was even better. It was better like dumb and dumber was it was better than the than the previous better one which was better than all the other ones because you could not snort it and so forth. you couldn't abuse it and the actual hardcore drug addicts didn't want that stuff. I but um but my my point is about the settlement part. Um whether you I don't know it's really more kind of recent thing. Um but I it feels feels to me like they went after um Wreckit Ben Kaiser um because they were pushing this thing but they were asked to push it through the data 2000 act the drug addiction treatment act 2000 under Bill Clinton. So I don't know if you want Well, they weren't asked to push it. They were they were simply allowed to. But that's you're entirely correct in that there are very strong parallels in between record Bener that then turns into indivce like the heat really starts coming down from the DOJ the department of justice uh investigation and Purdue. Those those parallels are made explicitly clear in the 2020 um sentencing of of Sean Thaxter who was then uh RBP's recorder pharmaceuticals RBP's um at/indivor's CEO what um what RBP did with Suboxone which is their version of bupinorphine that was uh explicitly allowed to through the data 2000 the drug abuse and treatment act of 2000 which was signed into law by Clinton uh President Bill Clinton in um I believe it was October of 2000. It was the first time that physicians were allowed to prescribe maintenance medications in American history in about you know 80 plus years since the 1914 Harrison Narcotics Act cut down on that availability and of course since after the morphine clinics that were somewhat widely available after World War I and then got shut down in the 1920s. Once those closed, um, there was no, I mean, like, uh, David Herszburg, who is a a drug historian up at the University of New York in Buffalo, he wrote a great book called White Market Drugs, and he found that there was a little bit of underground opioid maintenance um, going on after the after the Harrison Narcotics Act and after the morphine clinics across the country closed, were sort of forced to close in the 1920s. The last one finally closed in 1923. But of course, this is very small. It's very low level and it's very very very underground. So this stops for about 80 years until it's resuscitated and revitalized by the data 2000 act. And that act simply allowed physicians to prescribe controlled substances in schedules 3, four or five for opioid maintenance from their private um from their private offices. uh private uh private far uharmacies were allowed to distribute these drugs. But it made no specific it it didn't name buprenorphine. It didn't name Suboxone. It didn't name recordbenkeiser pharmaceuticals. It simply said those substances in three, four or five, schedule 3, four or five were allowed to be prescribed for this purpose. The only drug that was in schedule 3 that could [laughter] be prescribed for maintenance of course was buponorphine. Now recorder actually made two formulas of the drug. One was a purebupinorphine formula called Subutex and they never really focused very much on that. Now data 2000 says that it's you're allowed to prescribe it but that was very much withheld and sort of uh quarantined to specific circumstances like women who are pregnant um ERS things like that. It was never a big seller. It was never the focus of the company. Suboxone was very much the focus of the company. And that's a different drug that is four parts buponorphine combined with one part nlloxxone to uh avert misuse of the drug because if was someone was to now remember back in the 90s and early 2000s the only formula available of this drug is a is a tablet and it has to go under the tongue it has to be distributed sublingually because if you swallow buponorphine it's neutralized by the liver and it doesn't work. So there were these sublingual tablets that uh reports actually across Europe in the 1980s when people when it was available simply as an analesic people were crushing them and injecting them and using as a recreational drug and that was very much not the point right but so what re what Beniser do uh record Beniser pharmaceuticals was trying to do in the early 2000s was promote suboxone as the first maintenance medication to be available from a private physician in 80 years with this abuse used deterrent through the addition of that one part in a lock zone. And they were actually going for a very different consumer at the time in the late '9s when all of the lobbying is going on to pass data 2000 and shortly after the drug is approved by the FDA in October of 2002 and then once it comes on the market in 2003. They're not going for a prescription opioid user at that point. They're actually going for the rising number of middle class and teenage heroin users because in the '9s there was a massive amount of very pure and relatively inexpensive heroin being trafficked to the United States from places like the Middle East and Asia. Uh and that has brought a new level of heroin use to places like the middle class that here24 had not been very interested in the drug. They were always turned off by injecting. They didn't want to use the needle. But as soon as it was pure enough to snort, heroin started rising. And you see this in the 90s with like the heroin chic um uh fashion phenomenon. You see it through the deaths of uh people like Kurt Cobain and the use of heroin use of people like Perry Ferrell and all these other musicians. So data 2000 passed as a sort of I guess you could say public health response to rising rates of heroin use among the middle class and teenagers. people who either were not allowed to go to a methodone clinic because methadone clinics aren't really allowed to treat treat people under the age of 18 or people who would refuse to go to a methodone clinic like a middle-ass person who's not going to stand outside of a methodone clinic at 5:00 a.m. every single day. Uh so it was not necessarily created to become a commercial bestseller. It was not necessarily created to only support, you know, suboxone and buponorphine and things like that. But data 2000 opened the door for this drug to enter into the marketplace and it really kind of takes off as a blockbuster phenomenon. Gosh, almost a decade later, once is starting to be targeted toward that uh that prescription opioid use uh user and also once you have a mass influx of the former salespeople from Purdue who used to be selling Oxycontton, they all get laid off in the early in like the mid 2000s because Purdue is coming under fire from a numerous amount of lawsuits. And once they shed all of their sales force, RVP sucks them all up and starts to have them to sell um Suboxone instead to this rising number of of prescription opioid users instead. And that's where it becomes a really a commercial commercial enterprise especially once you lift the patient cap. So remember also in data 2000 uh doctors were limited to 30 patients a piece. So it was a very limited patient population that that is raised to 100 patients a piece in 2006 because of the escalated uh escalating prescription opioid crisis. And as soon as you get like 100 patients per uh physician cap, that's when it really becomes this sort of like hardcore commercial enterprise. But it did not begin that way. really did start as a I mean the guy who started it Charles O'Keefe who is the president of record banker pharmaceuticals here in the US I've talked to him multiple times he's not this hardcore driving capitalist who is out there to exploit all these individuals he really did believe in the drug he believed in the power of buponorphine he believed it had the power to bring I mean if you have a million heroin users in the United States in the in the year 2000 and that's what you know it's like a million to 1.5 million those are what federal estimates suggested And there's only 800,000 attending or not even that actually like less than that attending methadone clinics. You have h far fewer far fewer right like 80,000 or something sorry take away a zero like 80,000 you have a whole lot of people who are out of treatment who need assistance and what he envisioned buponorphine being as something to kind of assist this large you know majority of people who are are cannot access um cannot access addiction treatment or don't want to um so he came to it with like a with a different viewpoint but it became something very different Yeah. Um, you know, as far as the the blind men and the elephant, you know, I kind of see this a little bit differently, and I don't want to be confrontational here, but, you know, you did bring up a few interesting points. Uh, first of all, about the marketplace aspect. Um, you know, price of heroin going down brought more heroin users. Um, and and and while we're doing little parables, I don't know if you know the song Little Old Lady Who Swallowed the Fly. Do you know that song? Oh, yes. I have I have I have small children, so I hear it fairly often. I [laughter] I love that song. I thought it was a book. I I remembered it as a book, but there's not really a book. Apparently, more of a song. There is a book. Uh she swallows a fly. Uh it disturbs her, so she wants a cure. So, she swallows a frog to eat the fly. Of course, eating a frog is not that great hopping around in her belly. And so, she has to swallow a cat to to eat the frog. And then she has to swallow a dog to eat the cat. And every time her belly gets getting bigger. It's a so hilarity ensues, right? It's a great song and it's great for kids and so what um but you know the marketplace I mean you you bring up kind of I mean the essence of your book Addiction Inc. uh is that there's an incorporation aspect as a like a privatization and a profit motive and you use the word exploit a couple times. Um I I I think there is exploitation there of a sort um but I think it's it's um more of an annealing with the private and public um marketplace. I think the public paradigm change uh created a private marketplace and I also think the public institution and and um distribution of of an ancillary narcotic whether it's methadone or bupinorphine and so forth and you say not distribute you know either pre-rean or post reagan one form or another there's there's you know essentially free narcotic poured into the system form of methanone um it's not there's no outside marketplace not being sold on the streets not really um you know treat you know a standard kind of treatment something else. Um, but you know, if you are in that system, you're disabled or you're on Medicaid in one form or another, you're going to get medic, you know, methadone and whatnot paid for. And so there's a whole institution there, whether it's, you know, the strictly public health kind of version under Nixon, etc., or more of the privatized version of SAM under Reagan, whatnot. There's kind of an ongoing expansion of methadone, which did not like. So the the point I make is, you know, I don't think it necessarily, you know, made the pre-urs wild heroin dealers of the 70s become travel agents, um, accountants, um, PhDs in in, um, economics. I I don't think it changed them. I think they just went to other markets and I think they they expanded the marketplace. So, let's say, for instance, you're the heroin guy and you have a whole bunch of heroin on your shelf in your in your safe and under your under floor planks like Breaking Bad or whatever. you got a whole trove of this stuff. Um, and then they come along with methanone. They're going to take away your best customers, say, and they're going to put them they're going to give them free narcotic in a clinic. You know, what do you do with that stuff? It's all of a sudden you're not you're not going to donate it, you know, sell and donate it to Mother Teresa. You know, you're going to find places to sell it, you know, so you can sell more because that's your business model. And so, you know, what happened, you know, in the institution of methadone is that the um the numbers expanded widely. you know, the the the the opioid epidemic we had, you know, in the 90s and whatnot, certainly bad like the three waves of the opioid epidemic, you know, um Oxycontton, um uh rise lowering heroin prices and then fentinel so forth. But but what's ignored is the fact that there really wasn't much of a heroin market at all, you know, in what David Courtright calls the classic era of narcotic control and right and it came about, I think, with the institution of methanol. Anyway, so I apologize for the diet drug, but um what do you think about whether kind of the secondary marketplace that's stimulated that makes the dealers again not become travel agents and lawyers and whatnot, but stay drug dealers and just find different marketplace and so forth. What do you think about the that that kind of idea of the kind of the market expansion? Well, I think there's a lot of historical support for it. You know, I mean, I think you can see the exact same analogy with the cocaine market turning into crack, right? Cocaine in the early 1980s was extraordinarily expensive, prohibitively expensive, right? It was more expensive than a gold. Um, but when you combine that cocaine with a very cheap filler like sodium bicarbonate and some water and you turn it into crack and all of a sudden you make it widely available on the street for$5 or $10, that expands the user base and of course it also expands the problem it's it's causing. Um, I mean this is this is going to happen no matter what. This is something that Percy talks about a lot, right? If you expand the amount of opioids available, the opioid pres the opioid problem is going to is going to increase. I don't have any argument against that, but I do think that there were a lot of people at least in the late 90s and early 2000s who were interested in addressing rising heroin use because even though it was small, it was still rising and like there there there were issues with heroin in the 90s, right? It was it was becoming an issue. I I totally agree. Yes. Right. But there there weren't problems in the 50s and there weren't really problems in the 60s. Oh god, no. But but of course you had World War II destroying global trafficking networks. Well, there were no problems in the 30s. There was no problem in the 30s. There was no problem. Yeah, that's true. There was no problem in the 20. You know, the the classic era goes from the 20s with prohibition. Um up until up until really the 70s um the 60s, whatever. And and you know, you you covered Vincent Dolan, Marie Niswander, however you pronounce it. Nice one. Nice wander. Think about like you're taking a nice wander through the water. It's nice and Mary Mary Gene Crick I think it is um Creek. Yeah. Uh and that the interesting triumvirate at Rockefeller University. Um they they came up with this methodone idea but but it wasn't instituted to treat drug addiction. Um it was instituted to reduce crime. Um well that's it's both. I mean it it it is both, right? And I don't like sometimes I feel like people really glom on to this idea that oh it was just to reduce crime but of course like it was but reducing drug addiction and crime simultaneously. I don't think that they ex each other out and you I like if you go back to kind of like you put yourself in that moment of like the the mid1 1960s into the late 1960s when crime was escalating like out of control. I mean like cities are burning. It's not a bad idea necessarily to want to reduce crime. Now, the connection between drug use and crime is axiomatic at the time and today. And as I wrote about in my book, treatment doesn't necessarily bring down crime. But I don't think that using like politicians and for the most part doctors like they're not going to do a lot of things without something to justify their involvement. and politicians particularly really want to have like very concrete um concrete objectives that they can achieve and bringing down crime is a huge one. That's what literally got Nixon into the field in 1971 was the 1972 election was coming down and he sure did have to bring down crime which sure was rising in the late 1960s and early 1970s. Uh so there was a a use of drug addiction to bring down these levels but it was not the sole cause. There were a lot of like Dole and Nice Wonder I found in my research and talking to Dole's son and talking to people who are connected with them. They were very they were good people right they were benevolent people they like they cared actually like Nice Wonder especially who had a Freudian psychoanalysis clinic for 10 years in East Harlem. She was working with these people not because she just wanted to bring down crime because she was some kind of like Rudy Giuliani like let's let's get this taken care of but because she actually cared about these individuals and bringing down their crime was simply part of it. Yeah. You know caring is is wonderful. Um there are a lot of caring individuals but uh I I like to look at effects. I I'm kind of a Giuliani Fran fan. I grew up in New York City and you know my teenage years were in the 70s. I got mugged a couple times in subways and Yeah. You know it. You know the crime. Well, but Giuliani, you know, didn't have a magic wand, but he changed my New York. You know, my New York was was one that's a lot more like today. You know, it's more like the 201s and 2020s and so forth. Um, there was, you know, was the flowering graffiti. Um, we didn't have homeless on the streets, I have to say, to the same extent we have now. We didn't have those scaffoldings around the buildings. Uh, a few differences. And immigration was different. It wasn't, there were some, but it wasn't like massive. So what but but you know Giuliani made New York a jewel. It was it was a people were avoiding New York City. There was all this flight from the city urban flight in general. You know Detroit was kind of the paradigm for this. You know people just left the city. They were and and Giuliani rejuvenated and it wasn't that hard. You know you can argue about his methods. I don't think they were that draconian. It's not like um you know like El Salvador had huge crime just a couple years ago and and um Kelly you know stopped crime. I mean, you know, it sometimes you have to break a few eggs or whatever, you know, and I'm I I I put this out as a separate issue, but you know, I'm not a Mauist by any stretch of the imagination, but um um you know, I kind of hate Mao. Um and I hate everything he stood for. I hate these uh you know, what do they call them? Those struggle sessions and whatnot. I I hate the cultural revolution. I hate all kinds of things about Mao. Anyway, um but Mao adopted came into a country in 1947 that was riddled with opium and there was a huge heroin addiction problem and opium and all that kind of stuff and um you know he was a less nice guy than Giuliani and he started hanging uh opium dealers and heroin dealers and so forth and and he didn't hang that many. I think they were in the handful of hangings. Um I'm not sure what the the you know like a murder of crows. um you know I'm not sure what a you know how many hang hangs hangings he did but but basically the the whole opium problem disappeared you know this there's this thing where there's a permissiveness um you know so you know there's a lot of that Vincent Dole espoused the disease model he actually called it a metabolic disease opiate yes use now he did this with zero data and zero formulation never described what the metabolic problem was aside from the fact that people were using opiates fine um but well but they didn't know about the opioid receptors at the time I he's writing He's writing about the metabolic disease in the mid 1960s and he was basing that off of his study and he was I mean he was someone who researched obesity in the human body prior to this point. He was simply I think translating his previous research current research on I I I I disagree with formulation. I mean we we you know we have food receptors but you know we don't have disease by eating food. You know it's like you know you you can put a disease model on almost anything that we do. I mean I I you know I like playing sports and I like getting a runner's high. doesn't mean I have a disease per se doing that anything, you know. Anyway, so there's like I'm kind of veering away from a question here and I apologize, but um you know I I suppose the question would be since we're on Vincent Dole and and Nicewander um nice wander. I'm sorry. Um yep, nice wander through the woods. Yeah. Um you I guess we we done with crime. I mean, Jerome Jaffy like said in Senate hearings that that this was a a a program to reduce crime. Um, you know, crime wound up growing anyway. And I guess we're talking about Giuliani and draconian aspects and so forth and and kind of the ethos of the of the and spirit of the time. You know, there there's kind of this kind of movement one way or another about liberalizing rules around narcotic usage. Um, maybe we could talk about some of the experiments that have been happening. I I know you're familiar with Switzerland. Um, I think Zurich had a needle park and uh probably uh one in uh Lisba in Portugal and so forth. Um you know, Portugu Portland, not Portugal, but Portland, I think legalized heroin a few years ago. They undid that. Maybe we could talk about kind of the ethos and spirit of you know, where we st sit on this field. I mean, it seems like there's a few different pendula that are swinging back and forth. Sometimes they hit each other. For sure. For sure. Well, yeah. How do you want to approach the subject? I mean, [gasps] Oregon is Oregon was such a disaster. [laughter] Like Oregon, Oregon's experiment with decriminalization was such a mess. Um, and I think that actually speaks really well even to something we were talking about earlier, which is a versus a a national even versus like a state-based response. Oregon was I was talking to a buddy of mine at the ACLU. I think it was like 47th or 49th out of the country out of 50 states to uh for for treatment availability. And what they did in I believe it was 2020 or 2021 when they decriminalized the possession, personal possession of of all intoxicating substances was to allow people to take either a $100 fine or like call a number and then go be placed into treatment rather than being incarcerated or punished for for their drug possession and use. In theory, we've seen it happen in other places, and it's a very kind and wonderful idea, but you cannot put the cart that far ahead of the horse. Oregon did not have the infrastructure in place to actually create organizations where all of these people could be funneled into. If it's not the prisons, which obviously do exist, they can't go to treatment facilities that aren't there. So what it allowed for was simply the acceptance of open air drug use with no no remediation or uh or responsibilities whatsoever. And very quickly the entire state was like this is awful. It's really really bad. Now of course it was combined with a pandemic with um housing crisis with the rise of fentinel. I mean it was it was a perfect storm for a whole lot of things to go wrong but Oregon was not in a place to actually allow this to occur. And of course they're they they kind of had to eat their words. And um most of drug possession was recriminalized in I believe 2024. But that's not like you can't go about it in this way. And there's also like a very different cultural construct in Oregon versus Portugal, you know. Well, I know it's always it's always the the phrase about communism has never been done right. You know, there everything every time it fails because it's never been done right. I I think that there's, you know, a little bit of excuse making about it. Um I I I am not a harm reduction kind of guy. I I like the words. I like reducing harm. I spent my whole life trying to reduce harm in an individual basis. Not just for myself, but my patients. I want to reduce the harm they might have from some future illness or the harm they might have x y and z. But the concept as a public health maneuver, harm reduction has um whatever benefits it might have collectively, it it takes away incentives for for growth individually. Um what's what's an example? Well, you know, the one is like say condoms in the middle school. um there the idea is well we don't want teen pregnancy we don't want um I don't know teen veneerial disease whatever we don't want this we don't want that so we will put condoms in the middle school and and you know if you ran a Catholic school and I I think this is instructive actually because cath religion kind of falls into the addiction realm in a sense I mean the the the drug addiction rate amongst Mormons practicing Mormons is effectively zero um and and the same you know they're they're genetic conjuners you know in the Midwest in mountain states or whatever, you know, have a much higher uh drug rate as well as alcohol and whatnot. So, you know, religion is kind of not quite it is it is a church that specifically does not allow for it. It's like very similar to the Seventh Day Adventist church which is like huge around here no alcohol, no caffeine, no meat. I mean, if you have a religious imposition that says you are not allowed to do these things, that's a pretty strong motivator. I Well, I understand that. But that that's to the point of what we need to fix this. You know, a lot of these things are kind of replacement drugs. So, they're getting to the harm reduction model and again condoms in the middle school. You know, there's there's a Bob Newhart um episode. Uh the late great Bob New Hart. Uh company comes in for his office. She had a problem XY andZ. And he's like going to give her advice. It's like he's only going to need $5 going to be three minutes. She's like, "How can that be?" He's like, "His advice, cut to the chase." He's like, "Don't do that. Stop that." You know, this hurts. Then don't do it. Yeah. Yeah. But but it's like what we've done said in in because the we have nice people you know Marie literally named nice wander um you know people have with with kind of um softness in their heart and the grace of of wanting to help people doesn't mean they always do and it doesn't mean that that their ideas can translate into policy and and and people are funny things you know they sometimes go counter to the way that that the help would be there you know so that if we give some if you again if you have free condoms in middle school. You know, the message to the middle schoolers is, "Oh, we haven't been having sex. We should there's condoms. They're expecting us to have sex." You know, you know, every time they've improved the helmets on snowboarders and every time they put on better braces and and you know, better this and make things the sport safer, the snowboarders jump from higher heights. You know what we see now? We have a you know, people bicycling down mountains, whatever. You a lot of the times that we think we are reducing harm. What people actually want is the thrill and they they they go up to the edge of where the thrill is. If you draw the line here, you have kids, you know, you draw the line here, they they want to go there. And if you if the line were there, they want to go the thereer, you know, wherever it happens to be, they want to touch up against that because that is the essence of our discovery process. You know, as babies, we put everything in our mouth. We feel the world through our tongue and whatnot. And over time we have to experience the world a lot. I'm not I'm not recommending you know kind of freef fall for people. But I'll just put this out as a kind of question and you know over the same duration. Have we seen an alcohol epidemic? You know alcohol is freely available at a liquor store you know bartenders and wherever um and even amongst teenagers and so forth they can all find and get it. You know people alcohol is dangerous you know in excess and whatnot. to be a deadly and frankly alcohol withdrawal is more deadly than narcotic withdrawal but we don't have a government apparatus. Have we seen the same kind of expansion in alcoholism andor you know an opioid excuse me an alcohol epidemic when it's not something that the government has you know had some kind of cure for you know by by virtue of of of you know kindness and so forth. Well I mean alcohol deaths are about 178,000 per year. cigarette deaths are about 480,000 per year and we're just now below 100,000 opioid over or drug overdests per uh drug overdose deaths per year. So it's I mean it it's kind of like this is an issue I have with the people who are are very gung-ho just for legalization. You know, it's like well if we just legalize all drugs then you certainly have them under control and and regulations and things like that. And I don't necessarily believe with that believe that. Excuse me. Um, I'm sure you're familiar with the the iron law of prohibition, uh, which was, um, Dick Cohen wrote about that in the 1986, uh, National Review article. And then he actually went on to become the executive director of Normal, the National Organization for the Reform of Marijuana Laws. He was like the only sort of like uh, conservative Republican uh, executive director in the organization's history. But he argued, and a lot of people kind of glom on to this, that uh when a drug becomes prohibited, it becomes more powerful because it's easier to traffic a very small amount of fentinyl that can get 40,000 people high as opposed to a very large amount of morphine or opium, which is bulky and, you know, like it's very hard to hide in in, you know, like your clothes or your suitcases or whatever. And that's true, but there is just as much an iron law of legalization. And I think we're seeing that specifically in the realm of cannabis legalization. And we saw this in the realm of oxycodone legalization. The only reason we went from a 20 to a 40 to an 80 mgram tab of oxycontent was because Purdue Pharma was allowed to legally market these things. And the only way we've gotten to like 25 to 30% THC cannabis flour and 99% THC dabs is because of the legalization of the cannabis. these things are very very powerful because there's a whole lot of economic initiative behind that to make them powerful because people are always looking to push the edge. I think that's I think that's entirely true but I don't think that necessarily takes away the need for certain forms of of treatment or rehabilitation necessarily just because people are always trying to push the edge. I do think that that treatment of and and rehabilitation should be available to them even if they are pushing the boundaries. And the thing is like you're always going to have a lot of organizations and entrepreneurs who are seeking to profit off of and I hate to use the word again but exploit those individuals who are looking to push the boundaries. And 99% dab is not for like the like the user who's just like I want to relive my college days and smoke a joint. Those are for that, you know, it's like the 8020 rule, right? like um 80% of the sales of most intoxicants go to 20% of the most like sort of uh the highest the highest level users. And so I'm interested in in what you would then say if you know how how does one respond to uh a situation like this because I mean I think we've learned from the past couple of decades in the United States you can't necessarily just arrest your way out of this problem even in dealers and things like that. You don't arrest you don't arrest everybody. So uh have you been you choose to arrest then. Okay. Have you been to Japan? No, I was in South Korea in August though. That was fun. Well, does South Korea have maintenance narcotics? Gosh, what a great question. I don't know. But they um certainly alcohol is widely available. Cigarettes are widely available, but I think they have pretty harsh drug laws. I would say in Well, just to stay on topic, Addiction, Inc. is pretty much on the concept of opiates. Am I right? Hope you Yes. Fair enough. So, um, [clears throat] for my book, um, which I hope you will look at because I'd love to get your thoughts on it and maybe, uh, yes, you sent it to me. I started I I I was just dipping in before our conversation, so I'll go back and maybe you can get revenge on me. Um, you know, I I apologize if I, you know, give you, you know, kind of got you questions, but um, but I think you're good and and you're smart. Um, you can handle these things. Anyway, [laughter] um but uh you know for my book I was I was actually looking at Russia um which you know had we we had our kind of heroin moment from the Vietnam War um and it kind of got into our experience. I mean obviously heroin is predates this and you you bring up the interesting aspect of morphine clinics and you know morphine was there to treat opium and then heroin was there to treat morphine. Get back to my little lady swallow the fly. and um and methadone was there to treat heroin and in a sense buprenorphine is there to treat methadone. So you have is that five? I'm not good at numbers. Actually I think that is five. Um you know things in succession whatnot. Um but you know Russia had Afghanistan um their Afghanistan war uh I believe in the 70s and um they had a lot of you know there's a lot of dope in in Afghanistan. There's poppy fields and and um um heroin readily accessible. Um and they came up with a lot of addiction. So they had the same kind of ancillary problem. We had the, you know, the golden triangle. We had uh we we had troops in various times, Laos, Cambodia, and Vietnam. And uh there was, you know, not a lot to do there when you're off duty and and whatnot. People plus people were literally in pain here and there. And so they were doing heroin. And the the the image and actually the interesting um image from your book, I'm not going to show it here, but uh you have a Bill Sanders um the editorial cartoon. Yeah. Milwaukee Journal Sentinel in 1971. Uh he illustrated I have my book here. I can show it. [laughter] Fair enough. It's on uh if I can find it. Let's see what page is it on. It is on page 43. Um thank you. And uh so the idea is that uh you know we are going to be mainlining into the country. There's a needle and kind of these vicious devilish kind of uh fingernail monstrous hand. Yeah. Yeah. Is going to Vietnam. This is got this is we're going to uh you know there's the HL Mein said at one point uh dem theory of democracy is that people vote for what they want and they good need and they deserve to get it good and hard. I think the concept here is we got we got into the Vietnam War the Bard of Baltimore. I do love HL. Oh, it's great. And and so I think here um Mr. What is his name again? Um Bill Sanders. Bill Sanders. I think he has a little bit of um shenanoid towards the United States and we got into Vietnam. Well, here you're going to get this piece of Vietnam, you know, heroin injected into your body politic and bodies general so forth. Um, I don't think this actually happened. And I think a lot of the Oh, no, it didn't. Lot lot [laughter] the fright was there. I think I think Nixon a little bit got hoodwinkedked into the methodone concept because of the presumed numbers coming back from Vietnam. This was over and over. as a drum beat in the New York Times at the, you know, Erstwell, the Times, the Urswell Times or the Times, um, that this is going to some this is a ticking time bomb and and whatnot. Um, that that we're going to have all this massive influx of heroin addicts. And the fact of the matter is it it didn't happen. You know, there were heroin. It did happen for a variety of reasons. And one of the biggest reasons that it happened was because Jerome Jaffy, the head of the Special Action Office for Drug Abuse Prevention, or Seodap, just rolls off the tongue, um, instituted urine testing in in Vietnam. And you would not be allowed to leave the war zone if you tested positive for opiates. So, a whole lot of people stopped using heroin while they were still in Vietnam. And this was the biggest transformation in the field because if you think about it, prior to about 1970, 1971, the general medical consensus was that opioid addiction was a lifelong problem. You were never going to get off of it. This monkey was going to be on your back for the rest of your life. But what happened was as soon as he instituted urine testing in Vietnam with a brand new technology, the free radical essay technique or frat testing, which was allow which was this big bulky machine like you know the way like computers were in the 1960s, right? was a huge machine. But they brought two of them to Vietnam. One was in um Saigon, one was in um Long Bin, like the two main places that that service members were exiting the country. And a thousand service members are exiting every single day, right? There's about 300 service members who are there in like the peak of the war in 1970, 1971. And all of a sudden, you have to piss into a bottle and it's got to go through this little thing and it's going to show if you've used opioids in the past 72 hours. And if you have, you are not allowed to leave a war zone. There you go. And that's bad, right? People don't want to don't want to stay in Vietnam. So So what what they were able to do, what many of these soldiers were able to, and this is the difference between heroin use and heroin dependence/addiction. And Jaffy always knew this. He always knew that there was a difference. And he's like, if you can get the people who are simply using periodically to just simply stop once they come back to the United States, they're in a completely new environment. They're back home. They're with their family. They're with their friends. they probably will not continue heroin use. The people who do have an issue, the people who are addicted or dependent, who do test positive, yeah, they have to stay in detox in Vietnam, but when they come back to the US, there is services for them. And that's the biggest thing. There was no I mean, this is what comes from um gosh, why am I blanking? Washington University at St. Louis. Her name Lee Robbins. Oh, the woman. Thank you. Lee Robbins. She was this the report that she wrote after she followed 900 and some veterans returning from the US after this urine test and all this when she realized that heroin addiction or opioid addiction at large is not this lifelong chain that you have to wear around your neck and that was huge and but but no one had proven that before and it took an example like Vietnam to actually give people so the thing that that puzzles me is we have all these kind of dispositive evidence that this is not something you have to do forever but it But but if you read the press and if you recreate the New York Times of the times um in New York the times of the times yes well the uh [laughter] the times of the New York Times in New York um at the time of uh I can keep just I'll be here all day anyway um you will find exactly the opposite that this ticking time bomb uh image is is but that's the media firestorm. I mean that that well this has not been helpful you know I think I think this became a perfect storm. I'm not a conspiracy guy, but I am a conspiracy of interests guy. Uh, which is to say, the example I till I come up with a better one, the one I always use is I it's a hot day. I've got an ice cream cone and uh maybe it's soft serve and I'm walking down the street enjoying it and I'm like looking at something and all of a sudden hot it melts. It falls to the ground. Okay, the raccoons getting back to the raccoons or the flies, the insects, the ants. Um, I don't know. The little old lady's going to eat all of those, by the way. She's just coming for them. Exactly. all those animals, um, pigeons, whatever, they have no idea this going to happen. They're they're not conspiracy theorists about ice cream falling in this spot. It happens. And they once the ice cream's there, there's a whole apparatus and engineering going on. Who's going to get it the fastest? So, some pigeon's going to like try to whisk off at the whole thing. If it's a candy bar or whatever, and the answer, if it's if it's liquid, they're going to be in the cracks that anyway, there's a whole operation to deal with the fact that I dropped the ice cream cone. So nobody had the pre-ordained notion. There was no conspiracy about this happening. I didn't think I was what I was going to do. It just happened. But once something happens, once there's an attractive nuisance um or moral hazard, I guess you'd call it um there then then something happens beyond that. And so I think the the the inst the conspiracy of interest where a few different things happening confluently um in in our world, you know, Vietnam and this kind of concept that we had to get it good and hard for having violated, you know, whatever that the the Vietnam, you know, sovereignity, whatever we did, we had to be punished and and this whole drum beat about the the heroin thing is going to come bite us in the butt and the crime's going up and all this kind of thing. We need to have methanone maintenance because Vincent Dole had come up with this idea and Howard Sweet and nice you know Maria is and all kind of stuff. I think this was a bad idea applied and a wrong solution to a problem and I I you know you bring up Marie uh nice wanders work in Harlem. This guy Robert Beard are you familiar with him. I actually don't know the name contemporaneous. [clears throat] I have a Substack. I'll send it to you. I hadn't been either. I I found him researching for my book and uh it said Harlem doctor blah blah blah you know comes out against um you know the methadone clinics because he thinks it's going to bring more crime people are already addicted to stuff why add more you know narcotic into the mix all kind of stuff and I just assumed I don't know I assumed he was a local Harlem doctor but he wasn't he was an upper east side uh fill in the blank I think a diabetist he was endocrine guy and he was doing insulin and stuff and on his own. The guy's like a bleeping saint. I mean, he spent his nights going up to Harlem and with crime and all kind of stuff, driving the subway, whatever. Or maybe he drove his car, I don't know. But he he wound up in in East Harlem every night of the week and sometimes the weekends as well dealing with narcotic addicts and he he tried to get them unaddicted but he had group meetings and no drugs and he you know he might have I don't if he had anything palative or whatever but he his whole thing was to get them off drugs and he was just flumxed flabbergasted um etc etc that this was going to happen. he was, you know, yelling stop and and uh so I have a little piece on him does kind of a a payon to his his great work and totally ignored. Um but I don't think he was wrong. You know what happened was the the the rate the of heroin usage was highest in New York City amongst the whole country and New York City was the highest in Harlem Bedford the black neighborhoods not because they're black because they were poor they were they were had the highest rate when when it was like Italian and so forth because of the poorest area the poorest area in New York had the highest rate of heroin in the whole country because it's a port city um and that's that's where the stuff would land so the places where there were heroin problems through that era of classic control were Chicago uh New York LA in Fort Worth because on the you know the Texas border etc. And that's where the heroin was happening in so far as it was happening for those that duration and and the the rate was highest in the black population and over you know over the succeeding 20 years um the rate in Harlem was no longer higher than the rest of the country. So that sounds great but that's not because the Harlem rate went down. It's because everybody else went up to Harlem's rate. basically we Harlem was up here and all the tide everybody else wound up at Harlem's rate of narcotic usage and heroin use and so forth. So, you know, I kind of feel like that the, you know, we can we could talk about answers and solutions. Uh, but I feel as if this hasn't been it. You know, as if kind of the the harm reduction approach and that that you know, certainly, you know, we we know people who die from from opiates and that's tragic. Um I just don't know if we've applied the right answer to it given that say getting to Japan and and or Russia. Um that Japan does not didn't have an opioid epidemic. They didn't for the whole duration of our you know whatever you want to consider the 90s and zeros and whatnot. Uh they didn't have it you know and Russia didn't either. You know they Russia's got loads of problems. Don't get me wrong. I I wouldn't trade places with being in Russia. I might if I were Japanese to you know trade in Japan. I don't want to learn the language but if I whatever but but you know there are places that are there experiments being run right now they're called other countries that don't do this and frankly amongst our states we have other states that don't do it you know Wyoming does not do it um it's small place it's hard to you know get much data from that but Mary Jane Creek you know in one of these memorials to methadone and and self- congratulatory you know she she feels that that what we need is is universal mandatory maximum access to methadone um but of course that's not What the that was not the only thing that Seodap was promoting at the time when they were really in power from 1973 or 1971 to 1973. It all kind of fell apart in 1974 with everything else that fell apart in the Nixon administration with Watergate. But that this was not what necessarily Seab's emphasis was. It's by far the most controversial. It's by the it's the part that got them the most flak. It's the part that turned Jerry Jaffy into like a a sort of you know hated person in Washington. But methadone clinics that they were funding at the time were only about onethird of the clinics that they were funding otherwise. They were funding a lot of other programs, a lot of abstinence-based programs, detox programs, counseling, therapeutic communities, halfway houses, all of this other stuff. We hang this albatross around Seodap and Jerry Jaffy's neck saying, "Oh, you're Mr. Methadone and you're pushing this on the country and blah blah blah." But that's not what he was doing. He was um he was a big proponent of what he called multimodal treatment options. It was what the person wanted and could help them the most and that was simply to be made available to them at the time. Now remember, methadone is still very very new. In the 1970s, in 1970, I found a report that only 9,000 patients were on methodone maintenance in the United States and Canada combined. In 1971, that does increase because of SEOP support for methadone clinics. And that increases to about over uh there's over 72,000 people in federally funded addiction treatment care by the end of 1973. But only a third of those patients are me are methadone patients. It's not this overwhelming this is our only response and we've got to cut down crime and blah blah blah. He was funding a number of programs. And there was so much controversy about methadone. People hated it, especially in the black community because you're like I mean you're coming at the end of all of those racial uprisings, right? people who are saying like you after the assassination of Martin Luther King and all this other stuff, they're like, "We want better jobs. We want better housing. We want better schools. We don't want to live in these slums. Like, why don't you take care of these problems?" And when what they get are simply like therapeutic communities and methadone clinics, they're furious. They're like, "This is not the response that we were looking for." And methadone has been controversial from that point on. But, um, Jaffy very much dislikes that he is only remembered for his participation in the methadone clinic system. And that was why the first six times I talked to him on the phone when I was embarking on this project, he would he he he was like, "You're just here to tell me how awful methodone is and blah blah blah." He would make me cry. Like it was just awful. And finally, I won over his um his I I finally won his his trust when I was like, "No, I've read all of your papers at the Library of Congress. I do not think you're just Mr. Methadone. I think you actually instituted a program that was much more responsive to the wide variety of needs of a wide variety of people who use drugs." And then he finally started talking to me and he was giving me a lot of his papers that he did not donate to the Library of Congress that he kept in his basement. And that's how I found out a whole lot about the other stuff. But it is not um the Nixon administration wanted to get reelected in 1972. And in 1971, you have a perfect storm of three things, which is rising rates of heroin use in the United States, rising rates of crime in the United States. and the media freak out about addicted soldiers coming back from from Vietnam, the GI junkie phenomenon, which of course did not materialize. But the Nixon administration simply had to respond. So they do bring in Jaffy out of nowhere. He's he did not realize he was going to be the nation's first drugs. He just kept getting invited to Washington and then all of a sudden he's put out in front of Congress and the and the press and he's like, "Okay, we have a new drugar and you're in charge of $155 million, twothirds of the federal drug budget. You better open as many clinics as possible." the the biggest number you possibly can and you better bring down crime. I mean, he had a huge job in front of him and to his credit, he actually did it. Crime did decrease in 1972. It was a blip, went back up in the in the later 1970s, but he got it done by supporting as many options for treatment as possible, not just methadone. And um he was a big big big supporter of Lamb, Lalpha acetylmethad. He was a big supporter of Nalrexone. He was a supporter of all forms of addiction treatment that would get people to the point where they were no longer living lives of desperation. Right? And that's that I think is probably the most important thing I want people to take away from my book and from this conversation. Like it wasn't necessarily just trying to get Americans on maintenance and keep them on it forever. There was actually a really fullthroated support for a wide variety of treatment options. Um, and we've forgotten those and we've turned pretty much all of those actually into like money-making exploitative opportunities today. And that's that's bad in my opinion. That's where I come down on it. Yeah. No, I think you and I can agree on certain aspects of this. I I'm sure it's not my only I I don't I'm not saying I'm the inventor of this term, but I use the term methadone industrial complex. And um I agree. I think there is an MIC. [laughter] Yeah. And I I wonder and worry whether there's also a suboxone industrial complex in a sense as well. There is. There very much was. And it was actively created by Wreckit Benkezer Pharmaceuticals under the direction of Sean Ther I I don't know that precisely. So with methadone, you know, there's no there's no pharma company, you know, there is one. There's Malenrot makes the stuff, but it's all behind the scenes. It's all like the Wizard of Oz, you know, somebody behind the green curtain, all that kind of stuff. Nobody sees methadone. There's not commercial. There's no methadone commercial during the Super Bowl and you [clears throat] know I don't I don't even know if there's a brand of methadone. There used to be Dolphin or whatever but you know methadone is not there's no pharma push for methadone. There's no public push for methadone and yet methadone has expanded year by year by year and decade by decade. Um it may have been tempered a little bit by suboxone as an alternative mo you know modality you know which dstigmatized methadone and got rid of the methadone clinic you know kind of stink whatever nobody want wants to hang out there etc. Um but it's not the methodone industrial complex I think has much more to do with physicians and institutions that own those clinics and so they have a business model which is very interesting. I have an article I hope to get out in the [clears throat] city journal or someplace called the Starbucks of narcotics and [clears throat] it basically narcotics. This the puditive title is star the Starbucks of narcotics that Starbucks narcotics I mean I think good pun here I really like that and so uh you know Starbucks in my theory would would love not only to be able to dispense coffee but to get $50 every day for for for you know having you drink it especially in front of them or whatever drink your coffee and down it and we're going to get I don't know 45 bucks from the federal government or state or whatever for doing it. So, we're going to get a fee. Now, caffeine is addictive and people you could argue that oh, there's no reason. I mean, I I don't want to give a good idea to Starbucks, but um you know, they they would love it. You know, cigarette manufacturers would love to say, you know, we have this addictive product and you know, we're going to make sure we we dose people the right whatever. So, but but on the other hand, methadone does and I think it has much more to do with addiction and public health and you know if you look up uh you know the goo Google book uh engram you know the frequency of term usage addiction um we think of addictionologists and I'm sure they have their conventions every year but uh I I was surprised to see that you know it only came into being I think in the 1980s and it just grew as a term that's not like diabetist you know somebody like this do Dr. Robert Beard literally was a diabetes doctor and diabetes as a term has been around forever but if you follow kind of the medicalization addiction um addictionology um these are relatively recent conception not addiction per se but kind of the treatment around it is is a new formulation and and getting to the little lady in the fly I think the more things we do for this sometimes it we're not necessarily making the problem better and and I think we have to kind of detox uh from a lot of the you know a lot of the uh ideas that we just think are there. You know, if you ask a fish what's water, you know, he might not have any idea because he's like swimming in it all the time. He doesn't understand water being poured or water turning to ice cubes or whatever, you know. Yeah, that's just his world is water. And so I think we are in a world where we think this is what we do. We have where, you know, methadone opioid, excuse me, um medications for opioid use disorder. You know, we've created this stuff. the these are things that align with the addictionology, you know, college fund, you know, if you're an addictionologist, you want to get your kid through college, you know, this this has been very very good for the concept. All of a sudden, again, bartenders would love this, you know, if they could not only pour the drink, but get paid 40 bucks for having seen you, you know, and bill it to some third party that you're not aware of and and taxpayers not aware of. This is I think the real blackbox warning that should be out there that the methodone is a black box. It's it's right in plain sight but and and and and I I would put a slash with buprenorphine suboxone that these things are out there and there's been a huge expansion of it and it's been on the taxpayer dollar for the most part and um and they've been growing and their their method is essentially you know like thyroid replacement like you know they use their analogy themselves all the time it's like di like insulin for a diabetic. I do not think this is the case at all. You know, if you haul up uh, you know, in an Istanbul prison like that, Midnight Express, you know, some two guys with needles and one of them is a junkie with heroin, one of them is an insulin um diabetic and you take away their needles because they're both bad people, whatever something, you know, the the diabetic dies in two weeks. That's it. And the the heroin guy is like feeling awesome in in four weeks, not two weeks. And so you know this this concept where we are treating this but we don't treat addict you know sex addiction we don't have you know we don't have replacement um you know therapy for Tiger Woods you know to get see hookers we don't have gambling replacement you know where you go to Las Vegas only twice a week you know we don't do that for any of the other addictions I think you know people are addictable clearly um to various things um but I I think we have this idea that we are helping people by helping them and sometimes they they are only helped when they you know craft their own exit and it's a it's a it's a difficult thing. Well, I think you should talk to Sally Satell. She's a doctor here in DC. She actually works in a methodone clinic and her book is coming out. I have the galley. Um uh not a disease. Oh, there you go. Rethinking addiction in the heart of America's opio overdose crisis. She went to uh she spent a year in Ohio, Iron, Ohio, I believe. And uh this book's coming out and I think she would be someone who you could talk to specifically about that kind of stuff because she I think is very much a proponent of that idea as well. Well, sort sort of I mean we've exchanged emails and without without revealing any private s I've been in contact with her for like more than a decade. Um and Sally's great. Yeah. I've never met her and I will asked to be on the show and u at first she said yes but that you know my ideas about methadone are not hers and so she works for a methadone place. I don't know. You know, I'd love to hear what her concept in that book is. Maybe you could report back uh to me or whatever. I don't want to get you to tell. I'll give you a full report, but but I think there's there's, you know, an interesting aspect like I I've actually interviewed I don't know if you know Theodore Dal Rimple. Do you? Um his he's writes for City Journalist. His name is Anthony Daniels. Uh he he eventually dropped the um the pen name a few years ago. It's a great pen name though. Oh my god. Yeah. He I he told me how and why he picked it. There's another story. You got to watch the show. Um, but brilliant man. I I he totally, you know, you know, he's kind of my idol. Um, and he wrote a book in UK called Junk Medicine. And here it's called Romancing Opiates, which is a less less good title, but if you want to find the book and uh he covers a lot of things that I saw in real life, you know, IRL as the kids say. Anyway, um I want to give you the last last words and I've taken a lot of your time and I apologize. Um, but I very much Oh, this is fun. This is a joy. Thank you for having me. This is great. Um, and uh um I like I could come up with a a last question. Um, but but why should people find and read your book and and again, you did kind of some of the take-home messages, whatnot. Um, where do you think the best place for us to go with addiction treatment would go would be? Well, I hope people read my book. It would be great if you did. My publisher would be thrilled. But I think we we treat substances like methadone and buprenorphine and nrexone as sort of these fixed ideas that they just sort of arrived in our life and in our community and in our society and that's just how they've always been and that's just how it is. But there is a whole lot of action and historical building that goes into creating the systems in which these drugs now exist. And my book exposes and explains exactly where those systems came from. And I think it's kind of interesting the fact that Richard Nixon in 19 on June 17th, 1971 created this federal office, executive level federal office to oversee addiction treatment in the United States and it spiraled into something now 56 years later which is radically different. Is it better? Is it worse? I mean, I think that's up to the individual to say, but I do hope that if people are interested in understanding how we got to this point that they read my book and they figure it out. I've been um really having a lot of fun talking to uh medical schools. I've been talking to federal offices. I've been doing some consulting for people who are interested in understanding the mistakes and the successes that we've had in the past and how that can influence the future of addiction treatment. Now, going forward, I mean, I am not a licensed medical practitioner. I don't know what's going to help, but I know a lot of people who have really benefited from that. I know a lot of people who are on it for a while and they've tapered off and they're living great lives. And I know a lot of people who are dead and I don't know them anymore because they're dead. But I do think that I I I I'm just on the side of the individual who's struggling, who needs help. And I'm a big fan of offering them a suite of options with sustainable and supportive people to allow that person to achieve whatever sustainable and supportive sense of sobriety and remission and recovery looks like. I am not here to grind an axe. I really just don't want my friends to die anymore. That's my That's my platform. It's a hill I'll die on to not see my friends die. That's it. Well, that's awesome. I'm I'm the one always grinding axes. I keep I keep a whole bunch you can't see them, but I keep a whole bunch sharp behind me. [laughter] You're a wood chopper. I get it. My wife here. My wife thinks grievance is my chew toy. And actually, it's not quite true. Um I I kind of enjoy the day most days, but there are things that I think uh need to be called out here and there and so that's somehow fallen to me and I'm I'm currently now an old um so um at the latter part of my career I kind of you know say what I need to say. Um anyway, thank you so much Emily. I it's been a pleasure. I hope I can have you on again um and uh discuss any slashall of these ideas and topics and it's been a complete pleasure and joy. It's been such a pleasure. Thank you so much for having me. I really enjoyed it. And as soon as you get like a hundred patients per uh physician cap, that's when it really becomes this sort of like hardcore commercial enterprise just because people are always trying to push the edge. I do think that that treatment and and rehabilitation should be available to them even if they are pushing the boundaries. And this is the difference between heroin use and heroin dependence/addiction. But there is a whole lot of action and historical building that goes into creating the systems in which these drugs now exist. So what it allowed for was simply the acceptance of open air drug use with no no remediation or uh or responsibilities whatsoever. We haven't done anything when we've had over 100,000 overdose deaths per year. Very few people understand that these three drugs. [music] [music] [music] Welcome. I'm uh here and honored to be with Emily Duftton. Uh she's a PhD in urban studies perhaps. Uh she'll maybe rectify that uh uh term, but she's a historian. She's the author of a few a couple books on addiction. Uh most recently, Addiction, Inc. uh Inc. period um as in incorporated and it came out University of Chicago I believe April of this year and it's an interesting read um she goes over the history of methadone and um I suppose maintenance therapy um principally concentrated in the 60s7s and beyond and um it has policy implications for today for uh narcotic and drug treatment um I thank you so much for being on Emily u what did I get wrong first of all and uh tell what [laughter] what what inspired you to to write this book? Oh, well, thank you so much for having me. I'm really happy to be here. Um, my PhD is actually in American studies, which is uh sort of a nebulous field of study. Uh, but for the most part, I focused on American history and cultural uh cultural history specifically. Um, I was inspired to write this book because I grew up in Allentown, Pennsylvania, which was very hard hit by the prescription opioid epidemic in the early 2000s. uh and a very good friend of mine passed away. He committed suicide by hanging himself um from a tree in the woods behind our old middle school after about 15 years of steady and escalating and increasingly chaotic opioid use. He was only using pills. He never injected heroin. He never joined in his roommate's use of meth, but he was very much a person who became extremely dependent on prescription opioids. And when he passed away, I was very uh upset by his death because he was a good buddy of mine and I really enjoyed his company. Uh and I was very confused by it because I thought he was one of the most vivacious person uh people I'd ever met in my entire life. And to lose him when he was just 30 years old was very disturbing. But of course, it wasn't just him that we lost. There was actually a number of people from my old high school whom we had lost to either um overdoses, opioid overdoses or uh suicides for a number of years to the point where you would go to a reunion and they were just getting smaller and smaller because our population was just being cut down. And I was really upset by this because it was a small high school. We were all very close and I was losing all of these colleagues and friends of mine. And so I had just published my first book which was about the history of cannabis activism for and against legalization from the 1960s to today. And I was kind of fishing around for another topic to write about. And I realized my friend Dana's death posed um kind of a research problem that I could start to maybe potentially write a book proposal for. So I started asking a lot of the doctors and researchers and experts whom I had come to know through my years of working in drug history um what they would have done if my friend Dana had presented for treatment. And this was back in the long ago days of 2018. And every single one of them unanimously said he should have been placed on medicationass assisted treatment which was the term for uh this protocol at the time. I know it's moved on to mode or mood medications for opioid use disorder, but uh I continue to use medication assisted treatment just because it was the term that was used by the federal government, scientists, researchers, doctors, and patients at the time. And I still think it's actually like a really good sort of all-encompassing treatment uh term. Um but they said he should have been placed on Matt, MAT, medication assisted treatment. And I asked what that was. I mean, I was familiar with some of it, but I wasn't deeply familiar with it. And they explained it was the use of one of three FDA approved drugs either methadone, nalrexone or bupinorphine uh in con combination with various other services to allow a person to move away from street or elicit or chaotic drug use into a form of recovery. And I was like, well, you know, sounds great, right? I'm coming at it from I have no medical background whatsoever. As I was saying to you before, the sight of blood makes me incredibly queasy. Um, but I was intrigued by this. I was like, well, what are these three FDA approved drugs? Why aren't they so well supported by the number of people I'm talking to? And of course, why didn't Dana get them or the number of other people who had died from my high school? Why didn't they get them? And that launched me on an 8-year process to dig up the history of these drugs, where they came from, who developed them, and why. and of course why they are not necessarily uh a strong or a sufficient enough response to our larger opioid epidemic today. And that's kind of what brings us up to and you're right, my book was released in April, April 13th of this year from the University of Chicago Press. So that's that's that brings you up to today [laughter] or six months ago at least when the book came out. Congratulations. I assume you've done the book too and interviews and so forth. uh what what's the uh this is not to just save myself time but what what's the question that challenges the most or you find most memorable what's the point that you want to bring to bear on on the public um for their knowledge and and where do you think their lacuna absence of of expression and knowledge on this topic is or are I think the biggest lacuna is that we very few people understand that these three drugs all three of them and including actually a fourth drug that was also developed under the umbrella of medication assisted treatment but we no longer use it today. They were all developed as a very radical public health program in the 1970s which over the past 50ome years has transformed into extraordinarily privatized profitering uh sort of commercial um expedition today. And that is not necessarily functional for actually treating the opioid epidemic in the United States. And it's too bad that we lost this public health uh sort of commitment to it. And I think we blame the wrong people and we don't fully understand the history. And that is sort of the I mean that's sort of the driving the the the driving uh force behind what I what I wrote. Um and why I'm trying to bring this history back into the public light. Yeah. You know the seven blind men and the elephant. You know that parable. Mhm. Sure. Yeah. I mean I you and I come at this a little bit differently. I'm not going to I'm going to kind of suppress my my natural urges um [laughter] for a little bit, but you know, I um um you know, I'm aware of the MIAT aspects and and the drugs that are in in use. Um I I'm not sure I agree with your conclusion, but this is kind of would be at the end of this interview, but um while we're on this topic, um you you the way I see it, the way I interpret your book is that um the kind of fall from grace was taking this MAT, this kind of at the time was methodone treatment. There were there were other things as well. was the LAM and and and Nrexen, but principally methadone for decades until bupinorphine came about um 2000s. Um but you see kind of the uh the fall from from grace as the privatization of methadone clinics. Is that right? I have that right? And and and similar along those lines, just to extend the question slightly, I apologize. um it would be that you would see the the model um being more uh state controlled and or federal controlled um to take the profit motive out of the methodone clinics. And so my my ancillary question on top of whatever you want to discuss about that would be how would that improve things? Well, I don't know if it necessarily would at the point at this point, right? I think is it's a little bit too complicated but I mean other countries are completely sufficient at providing a level of care whether it comes with MAT or not for opioid use disorder or any other form of substance use disorder that doesn't necessarily exploit patients and treat them simply as customers in a system to be uh you know to be sorted profited off of and I don't know if that necessarily needs to be federally controlled. The United States is obviously a far larger country than places like Switzerland or Portugal that do have systems like this in place. But I think on a state-by-state basis, you can make this stuff available in a non-commercial way. I spent a lot of time in St. Louis, Missouri, uh at the u at the um clinics that are run through ARCA, the assisted recovery centers of America through Percy Menses, who I know you know as well and you interviewed. Um he works very closely with the state government. He works very closely with a lot of other partners to provide resources to individuals who are seeking help. And he does not exploit these people. He doesn't make uh he doesn't make these programs available in a way where like you're charging every single day when if someone walks in the door. These are a wide variety of sources that include medication, but he mostly focuses on buprenorphine and nrexone, which is of course an opioid antagonist, so you're not necessarily on maintenance for the rest of your life. He also provides things like food, housing, job placement. Um, there's a wide variety of resources that are available to people in St. Louis and beyond through ARCA that I think are a model that other states could follow. The nationalized system that was founded in the US in 1971 is an extraordinary moment in American history, but I don't know if it's necessarily something that we could recreate now. I think there was like this moment and there were a whole lot of factors driving what Nixon was doing when he instituted this model, but I don't know if that's necessarily true anymore. We don't have the same models. We haven't done anything when we've had over 100,000 overdose deaths per year. Um, but I do think on the state level, especially with money that's coming through either the opioid settlement funds or through the state uh state uh uh federal funds that go through the states, there's a lot of options and opportunities to make treatment available to individuals outside of commercial entities that I think would be valuable to pursue. Yeah. So, um there's a lot there to parse. Uh hopefully we'll come back to to any or all of it. Um you did mention the settlement. So this is interesting to me. Um, I wrote an article on uh Purdue Pharma and I I'm not a you know, as a as a physician um you know before I I I wound up treating people with buprenorphine in the 2000s but before that I was uh um alive and well and and treating patients from the 1980s on and I had my own place in River Massachusetts 1987 on it's like a primary care office walk and whatever and so I had my regular codery of patients but I would have um kind of a little bit don't don't misinterpret this anybody, but you know, if you have a bright light out there in the in the summer, they're moths. Now, you may not want them, but they're attracted to the light. Now, there's a great great Norm Coleman joke about this. Uh, I recommend people look it up. It's with Conan and Brian. It's one of the great jokes of all time. Anyway, um, and so having a a clinic like that, a storefront clinic with walk-in aspects, uh, I attracted a lot of people looking for drugs. uh poly we call they call it poly pharmacy but really it's also poly doctoring um because they have uh frankly the opposite of lack of access they have complete access they have you know at the time it's called Medicaid cards then became mass health cards Massachusetts but it's basically they have you know formal welfare benefits um and they have cart blanch um to to see physicians and they would do that over and over again they would um kind of like um you know on the merry ground they collect the rings if that's still a thing um or Pokemon, collect them all or whatever. So they they would go from doctor to doctor and they would kind of stop at me and uh I actually heard later on that my term in their group was Dr. No, the James Bond villain, right? I kind of think of myself as Dr. No at all, but but they they just had Dr. No because I would say no because I had this thing where I while they were, you know, signing in, whatever, you know, it was kind of like there were things about them that kind of rang a bell for me. you know, they'd come from another town, they had pain that wouldn't be solved by just low-level percoet. They needed, you know, uh, higher level oxycontton and so forth. Anyway, um, but I would call smarteries and see that they had had prescriptions yesterday, for instance, for right 90 of X and 30 of Y the day before and what and it was kind of before computers a lot of this stuff. I mean, not quite, but before the the integration so anyway. Um but so that that's kind of a little of a background of stuff I do. But um you know and these people were these people were seeking um or various other pain addiction treatment. They would want Oxycontton or or something of that level. They wanted some higher dose um you know prescription narcotic um and they liked Oxycontton but it was Oxycontton anyway. So I'm I'm doing two things some from opioid painkiller but not like a not like a treatment drug. They're looking for specifically like a painkiller. Yeah. Well, yeah. And mind you, I think a lot of them were selling to be honest with you. They they were collecting and selling. So, they were scavenging. You know, I actually call it raccooning. It's my own term. I don't know if anybody else used it. Um, you know, raccoons are are reasonable animals out in the wild, but, you know, in the urban environment, they're they're they're tipping over garbage cans and hunting for what they can. This is kind of the raccooning aspect where you're collecting stuff. Um, anyway. Um, but so so that's kind of my own interaction with continent in the day. Um, but more recently, you know, I I re I re because Purdue paid out this huge settlement. Um, and I researched it and and and to be honest with you, I kind of feel like Purdue was scapegoed. Um, Oh, yeah. A bit. They were and they're not paying as much as they could. And there but there's lots of other people who are paying the money, too. Well, yeah, but but they went my only point there's a long roundabout. I apologize, but I think, you know, like Willie Sutton, you know, why did you rob banks? Because that's where the money is. uh they went after Purdue Frederick uh at the time or Purdue Pharma because they had been bestin-class. They were making kind of the boutique version of these narcotic pills and and their pills frankly were not the ones people were injecting and so forth. That didn't that wasn't really the basis of the injectable um crisis. You know, people were smooshing their their other narcotics and snorting all kinds of stuff. Um and they actually made an abuse deterrent formula. And I think they their actual component of the number of pills that people were overdosing on was was minuscule. was never like never bounded beyond like 3 to 4% of the total. So I think there are other characters but they were generic and they weren't making the profit margin anyway. So that that's a little bit of a preface a little bit about me and so forth but I apologize about that. But in Diviar, which is a a um a I guess a a submerger of Wreckit was wrecked Coleman originally. Then they made Buponorphine um as a as a um an analesic pain medication like a narcotic and then it became Wreckit Benkeeser. They they merged with like Swiss company or something like that. Dutch Yeah, it was a Dutch. Dutch. Thank you. Sorry about that. Um but you know in a in a sense it's exactly almost the same paradigm or parable of the Purdue aspect which is they did exactly what the government wanted. Purdue was asked to make an abuse deterrent formula. They did they made the perfect one oxycontton one I call it. Then they actually a few years later made Oxycontton what I call oxycontton 2 which was even better. It was better like dumb and dumber was it was better than the than the previous better one which was better than all the other ones because you could not snort it and so forth. you couldn't abuse it and the actual hardcore drug addicts didn't want that stuff. I but um but my my point is about the settlement part. Um whether you I don't know it's really more kind of recent thing. Um but I it feels feels to me like they went after um Wreckit Ben Kaiser um because they were pushing this thing but they were asked to push it through the data 2000 act the drug addiction treatment act 2000 under Bill Clinton. So I don't know if you want Well, they weren't asked to push it. They were they were simply allowed to. But that's you're entirely correct in that there are very strong parallels in between record Bener that then turns into indivce like the heat really starts coming down from the DOJ the department of justice uh investigation and Purdue. Those those parallels are made explicitly clear in the 2020 um sentencing of of Sean Thaxter who was then uh RBP's recorder pharmaceuticals RBP's um at/indivor's CEO what um what RBP did with Suboxone which is their version of bupinorphine that was uh explicitly allowed to through the data 2000 the drug abuse and treatment act of 2000 which was signed into law by Clinton uh President Bill Clinton in um I believe it was October of 2000. It was the first time that physicians were allowed to prescribe maintenance medications in American history in about you know 80 plus years since the 1914 Harrison Narcotics Act cut down on that availability and of course since after the morphine clinics that were somewhat widely available after World War I and then got shut down in the 1920s. Once those closed, um, there was no, I mean, like, uh, David Herszburg, who is a a drug historian up at the University of New York in Buffalo, he wrote a great book called White Market Drugs, and he found that there was a little bit of underground opioid maintenance um, going on after the after the Harrison Narcotics Act and after the morphine clinics across the country closed, were sort of forced to close in the 1920s. The last one finally closed in 1923. But of course, this is very small. It's very low level and it's very very very underground. So this stops for about 80 years until it's resuscitated and revitalized by the data 2000 act. And that act simply allowed physicians to prescribe controlled substances in schedules 3, four or five for opioid maintenance from their private um from their private offices. uh private uh private far uharmacies were allowed to distribute these drugs. But it made no specific it it didn't name buprenorphine. It didn't name Suboxone. It didn't name recordbenkeiser pharmaceuticals. It simply said those substances in three, four or five, schedule 3, four or five were allowed to be prescribed for this purpose. The only drug that was in schedule 3 that could [laughter] be prescribed for maintenance of course was buponorphine. Now recorder actually made two formulas of the drug. One was a purebupinorphine formula called Subutex and they never really focused very much on that. Now data 2000 says that it's you're allowed to prescribe it but that was very much withheld and sort of uh quarantined to specific circumstances like women who are pregnant um ERS things like that. It was never a big seller. It was never the focus of the company. Suboxone was very much the focus of the company. And that's a different drug that is four parts buponorphine combined with one part nlloxxone to uh avert misuse of the drug because if was someone was to now remember back in the 90s and early 2000s the only formula available of this drug is a is a tablet and it has to go under the tongue it has to be distributed sublingually because if you swallow buponorphine it's neutralized by the liver and it doesn't work. So there were these sublingual tablets that uh reports actually across Europe in the 1980s when people when it was available simply as an analesic people were crushing them and injecting them and using as a recreational drug and that was very much not the point right but so what re what Beniser do uh record Beniser pharmaceuticals was trying to do in the early 2000s was promote suboxone as the first maintenance medication to be available from a private physician in 80 years with this abuse used deterrent through the addition of that one part in a lock zone. And they were actually going for a very different consumer at the time in the late '9s when all of the lobbying is going on to pass data 2000 and shortly after the drug is approved by the FDA in October of 2002 and then once it comes on the market in 2003. They're not going for a prescription opioid user at that point. They're actually going for the rising number of middle class and teenage heroin users because in the '9s there was a massive amount of very pure and relatively inexpensive heroin being trafficked to the United States from places like the Middle East and Asia. Uh and that has brought a new level of heroin use to places like the middle class that here24 had not been very interested in the drug. They were always turned off by injecting. They didn't want to use the needle. But as soon as it was pure enough to snort, heroin started rising. And you see this in the 90s with like the heroin chic um uh fashion phenomenon. You see it through the deaths of uh people like Kurt Cobain and the use of heroin use of people like Perry Ferrell and all these other musicians. So data 2000 passed as a sort of I guess you could say public health response to rising rates of heroin use among the middle class and teenagers. people who either were not allowed to go to a methodone clinic because methadone clinics aren't really allowed to treat treat people under the age of 18 or people who would refuse to go to a methodone clinic like a middle-ass person who's not going to stand outside of a methodone clinic at 5:00 a.m. every single day. Uh so it was not necessarily created to become a commercial bestseller. It was not necessarily created to only support, you know, suboxone and buponorphine and things like that. But data 2000 opened the door for this drug to enter into the marketplace and it really kind of takes off as a blockbuster phenomenon. Gosh, almost a decade later, once is starting to be targeted toward that uh that prescription opioid use uh user and also once you have a mass influx of the former salespeople from Purdue who used to be selling Oxycontton, they all get laid off in the early in like the mid 2000s because Purdue is coming under fire from a numerous amount of lawsuits. And once they shed all of their sales force, RVP sucks them all up and starts to have them to sell um Suboxone instead to this rising number of of prescription opioid users instead. And that's where it becomes a really a commercial commercial enterprise especially once you lift the patient cap. So remember also in data 2000 uh doctors were limited to 30 patients a piece. So it was a very limited patient population that that is raised to 100 patients a piece in 2006 because of the escalated uh escalating prescription opioid crisis. And as soon as you get like 100 patients per uh physician cap, that's when it really becomes this sort of like hardcore commercial enterprise. But it did not begin that way. really did start as a I mean the guy who started it Charles O'Keefe who is the president of record banker pharmaceuticals here in the US I've talked to him multiple times he's not this hardcore driving capitalist who is out there to exploit all these individuals he really did believe in the drug he believed in the power of buponorphine he believed it had the power to bring I mean if you have a million heroin users in the United States in the in the year 2000 and that's what you know it's like a million to 1.5 million those are what federal estimates suggested And there's only 800,000 attending or not even that actually like less than that attending methadone clinics. You have h far fewer far fewer right like 80,000 or something sorry take away a zero like 80,000 you have a whole lot of people who are out of treatment who need assistance and what he envisioned buponorphine being as something to kind of assist this large you know majority of people who are are cannot access um cannot access addiction treatment or don't want to um so he came to it with like a with a different viewpoint but it became something very different Yeah. Um, you know, as far as the the blind men and the elephant, you know, I kind of see this a little bit differently, and I don't want to be confrontational here, but, you know, you did bring up a few interesting points. Uh, first of all, about the marketplace aspect. Um, you know, price of heroin going down brought more heroin users. Um, and and and while we're doing little parables, I don't know if you know the song Little Old Lady Who Swallowed the Fly. Do you know that song? Oh, yes. I have I have I have small children, so I hear it fairly often. I [laughter] I love that song. I thought it was a book. I I remembered it as a book, but there's not really a book. Apparently, more of a song. There is a book. Uh she swallows a fly. Uh it disturbs her, so she wants a cure. So, she swallows a frog to eat the fly. Of course, eating a frog is not that great hopping around in her belly. And so, she has to swallow a cat to to eat the frog. And then she has to swallow a dog to eat the cat. And every time her belly gets getting bigger. It's a so hilarity ensues, right? It's a great song and it's great for kids and so what um but you know the marketplace I mean you you bring up kind of I mean the essence of your book Addiction Inc. uh is that there's an incorporation aspect as a like a privatization and a profit motive and you use the word exploit a couple times. Um I I I think there is exploitation there of a sort um but I think it's it's um more of an annealing with the private and public um marketplace. I think the public paradigm change uh created a private marketplace and I also think the public institution and and um distribution of of an ancillary narcotic whether it's methadone or bupinorphine and so forth and you say not distribute you know either pre-rean or post reagan one form or another there's there's you know essentially free narcotic poured into the system form of methanone um it's not there's no outside marketplace not being sold on the streets not really um you know treat you know a standard kind of treatment something else. Um, but you know, if you are in that system, you're disabled or you're on Medicaid in one form or another, you're going to get medic, you know, methadone and whatnot paid for. And so there's a whole institution there, whether it's, you know, the strictly public health kind of version under Nixon, etc., or more of the privatized version of SAM under Reagan, whatnot. There's kind of an ongoing expansion of methadone, which did not like. So the the point I make is, you know, I don't think it necessarily, you know, made the pre-urs wild heroin dealers of the 70s become travel agents, um, accountants, um, PhDs in in, um, economics. I I don't think it changed them. I think they just went to other markets and I think they they expanded the marketplace. So, let's say, for instance, you're the heroin guy and you have a whole bunch of heroin on your shelf in your in your safe and under your under floor planks like Breaking Bad or whatever. you got a whole trove of this stuff. Um, and then they come along with methanone. They're going to take away your best customers, say, and they're going to put them they're going to give them free narcotic in a clinic. You know, what do you do with that stuff? It's all of a sudden you're not you're not going to donate it, you know, sell and donate it to Mother Teresa. You know, you're going to find places to sell it, you know, so you can sell more because that's your business model. And so, you know, what happened, you know, in the institution of methadone is that the um the numbers expanded widely. you know, the the the the opioid epidemic we had, you know, in the 90s and whatnot, certainly bad like the three waves of the opioid epidemic, you know, um Oxycontton, um uh rise lowering heroin prices and then fentinel so forth. But but what's ignored is the fact that there really wasn't much of a heroin market at all, you know, in what David Courtright calls the classic era of narcotic control and right and it came about, I think, with the institution of methanol. Anyway, so I apologize for the diet drug, but um what do you think about whether kind of the secondary marketplace that's stimulated that makes the dealers again not become travel agents and lawyers and whatnot, but stay drug dealers and just find different marketplace and so forth. What do you think about the that that kind of idea of the kind of the market expansion? Well, I think there's a lot of historical support for it. You know, I mean, I think you can see the exact same analogy with the cocaine market turning into crack, right? Cocaine in the early 1980s was extraordinarily expensive, prohibitively expensive, right? It was more expensive than a gold. Um, but when you combine that cocaine with a very cheap filler like sodium bicarbonate and some water and you turn it into crack and all of a sudden you make it widely available on the street for$5 or $10, that expands the user base and of course it also expands the problem it's it's causing. Um, I mean this is this is going to happen no matter what. This is something that Percy talks about a lot, right? If you expand the amount of opioids available, the opioid pres the opioid problem is going to is going to increase. I don't have any argument against that, but I do think that there were a lot of people at least in the late 90s and early 2000s who were interested in addressing rising heroin use because even though it was small, it was still rising and like there there there were issues with heroin in the 90s, right? It was it was becoming an issue. I I totally agree. Yes. Right. But there there weren't problems in the 50s and there weren't really problems in the 60s. Oh god, no. But but of course you had World War II destroying global trafficking networks. Well, there were no problems in the 30s. There was no problem in the 30s. There was no problem. Yeah, that's true. There was no problem in the 20. You know, the the classic era goes from the 20s with prohibition. Um up until up until really the 70s um the 60s, whatever. And and you know, you you covered Vincent Dolan, Marie Niswander, however you pronounce it. Nice one. Nice wander. Think about like you're taking a nice wander through the water. It's nice and Mary Mary Gene Crick I think it is um Creek. Yeah. Uh and that the interesting triumvirate at Rockefeller University. Um they they came up with this methodone idea but but it wasn't instituted to treat drug addiction. Um it was instituted to reduce crime. Um well that's it's both. I mean it it it is both, right? And I don't like sometimes I feel like people really glom on to this idea that oh it was just to reduce crime but of course like it was but reducing drug addiction and crime simultaneously. I don't think that they ex each other out and you I like if you go back to kind of like you put yourself in that moment of like the the mid1 1960s into the late 1960s when crime was escalating like out of control. I mean like cities are burning. It's not a bad idea necessarily to want to reduce crime. Now, the connection between drug use and crime is axiomatic at the time and today. And as I wrote about in my book, treatment doesn't necessarily bring down crime. But I don't think that using like politicians and for the most part doctors like they're not going to do a lot of things without something to justify their involvement. and politicians particularly really want to have like very concrete um concrete objectives that they can achieve and bringing down crime is a huge one. That's what literally got Nixon into the field in 1971 was the 1972 election was coming down and he sure did have to bring down crime which sure was rising in the late 1960s and early 1970s. Uh so there was a a use of drug addiction to bring down these levels but it was not the sole cause. There were a lot of like Dole and Nice Wonder I found in my research and talking to Dole's son and talking to people who are connected with them. They were very they were good people right they were benevolent people they like they cared actually like Nice Wonder especially who had a Freudian psychoanalysis clinic for 10 years in East Harlem. She was working with these people not because she just wanted to bring down crime because she was some kind of like Rudy Giuliani like let's let's get this taken care of but because she actually cared about these individuals and bringing down their crime was simply part of it. Yeah. You know caring is is wonderful. Um there are a lot of caring individuals but uh I I like to look at effects. I I'm kind of a Giuliani Fran fan. I grew up in New York City and you know my teenage years were in the 70s. I got mugged a couple times in subways and Yeah. You know it. You know the crime. Well, but Giuliani, you know, didn't have a magic wand, but he changed my New York. You know, my New York was was one that's a lot more like today. You know, it's more like the 201s and 2020s and so forth. Um, there was, you know, was the flowering graffiti. Um, we didn't have homeless on the streets, I have to say, to the same extent we have now. We didn't have those scaffoldings around the buildings. Uh, a few differences. And immigration was different. It wasn't, there were some, but it wasn't like massive. So what but but you know Giuliani made New York a jewel. It was it was a people were avoiding New York City. There was all this flight from the city urban flight in general. You know Detroit was kind of the paradigm for this. You know people just left the city. They were and and Giuliani rejuvenated and it wasn't that hard. You know you can argue about his methods. I don't think they were that draconian. It's not like um you know like El Salvador had huge crime just a couple years ago and and um Kelly you know stopped crime. I mean, you know, it sometimes you have to break a few eggs or whatever, you know, and I'm I I I put this out as a separate issue, but you know, I'm not a Mauist by any stretch of the imagination, but um um you know, I kind of hate Mao. Um and I hate everything he stood for. I hate these uh you know, what do they call them? Those struggle sessions and whatnot. I I hate the cultural revolution. I hate all kinds of things about Mao. Anyway, um but Mao adopted came into a country in 1947 that was riddled with opium and there was a huge heroin addiction problem and opium and all that kind of stuff and um you know he was a less nice guy than Giuliani and he started hanging uh opium dealers and heroin dealers and so forth and and he didn't hang that many. I think they were in the handful of hangings. Um I'm not sure what the the you know like a murder of crows. um you know I'm not sure what a you know how many hang hangs hangings he did but but basically the the whole opium problem disappeared you know this there's this thing where there's a permissiveness um you know so you know there's a lot of that Vincent Dole espoused the disease model he actually called it a metabolic disease opiate yes use now he did this with zero data and zero formulation never described what the metabolic problem was aside from the fact that people were using opiates fine um but well but they didn't know about the opioid receptors at the time I he's writing He's writing about the metabolic disease in the mid 1960s and he was basing that off of his study and he was I mean he was someone who researched obesity in the human body prior to this point. He was simply I think translating his previous research current research on I I I I disagree with formulation. I mean we we you know we have food receptors but you know we don't have disease by eating food. You know it's like you know you you can put a disease model on almost anything that we do. I mean I I you know I like playing sports and I like getting a runner's high. doesn't mean I have a disease per se doing that anything, you know. Anyway, so there's like I'm kind of veering away from a question here and I apologize, but um you know I I suppose the question would be since we're on Vincent Dole and and Nicewander um nice wander. I'm sorry. Um yep, nice wander through the woods. Yeah. Um you I guess we we done with crime. I mean, Jerome Jaffy like said in Senate hearings that that this was a a a program to reduce crime. Um, you know, crime wound up growing anyway. And I guess we're talking about Giuliani and draconian aspects and so forth and and kind of the ethos of the of the and spirit of the time. You know, there there's kind of this kind of movement one way or another about liberalizing rules around narcotic usage. Um, maybe we could talk about some of the experiments that have been happening. I I know you're familiar with Switzerland. Um, I think Zurich had a needle park and uh probably uh one in uh Lisba in Portugal and so forth. Um you know, Portugu Portland, not Portugal, but Portland, I think legalized heroin a few years ago. They undid that. Maybe we could talk about kind of the ethos and spirit of you know, where we st sit on this field. I mean, it seems like there's a few different pendula that are swinging back and forth. Sometimes they hit each other. For sure. For sure. Well, yeah. How do you want to approach the subject? I mean, [gasps] Oregon is Oregon was such a disaster. [laughter] Like Oregon, Oregon's experiment with decriminalization was such a mess. Um, and I think that actually speaks really well even to something we were talking about earlier, which is a versus a a national even versus like a state-based response. Oregon was I was talking to a buddy of mine at the ACLU. I think it was like 47th or 49th out of the country out of 50 states to uh for for treatment availability. And what they did in I believe it was 2020 or 2021 when they decriminalized the possession, personal possession of of all intoxicating substances was to allow people to take either a $100 fine or like call a number and then go be placed into treatment rather than being incarcerated or punished for for their drug possession and use. In theory, we've seen it happen in other places, and it's a very kind and wonderful idea, but you cannot put the cart that far ahead of the horse. Oregon did not have the infrastructure in place to actually create organizations where all of these people could be funneled into. If it's not the prisons, which obviously do exist, they can't go to treatment facilities that aren't there. So what it allowed for was simply the acceptance of open air drug use with no no remediation or uh or responsibilities whatsoever. And very quickly the entire state was like this is awful. It's really really bad. Now of course it was combined with a pandemic with um housing crisis with the rise of fentinel. I mean it was it was a perfect storm for a whole lot of things to go wrong but Oregon was not in a place to actually allow this to occur. And of course they're they they kind of had to eat their words. And um most of drug possession was recriminalized in I believe 2024. But that's not like you can't go about it in this way. And there's also like a very different cultural construct in Oregon versus Portugal, you know. Well, I know it's always it's always the the phrase about communism has never been done right. You know, there everything every time it fails because it's never been done right. I I think that there's, you know, a little bit of excuse making about it. Um I I I am not a harm reduction kind of guy. I I like the words. I like reducing harm. I spent my whole life trying to reduce harm in an individual basis. Not just for myself, but my patients. I want to reduce the harm they might have from some future illness or the harm they might have x y and z. But the concept as a public health maneuver, harm reduction has um whatever benefits it might have collectively, it it takes away incentives for for growth individually. Um what's what's an example? Well, you know, the one is like say condoms in the middle school. um there the idea is well we don't want teen pregnancy we don't want um I don't know teen veneerial disease whatever we don't want this we don't want that so we will put condoms in the middle school and and you know if you ran a Catholic school and I I think this is instructive actually because cath religion kind of falls into the addiction realm in a sense I mean the the the drug addiction rate amongst Mormons practicing Mormons is effectively zero um and and the same you know they're they're genetic conjuners you know in the Midwest in mountain states or whatever, you know, have a much higher uh drug rate as well as alcohol and whatnot. So, you know, religion is kind of not quite it is it is a church that specifically does not allow for it. It's like very similar to the Seventh Day Adventist church which is like huge around here no alcohol, no caffeine, no meat. I mean, if you have a religious imposition that says you are not allowed to do these things, that's a pretty strong motivator. I Well, I understand that. But that that's to the point of what we need to fix this. You know, a lot of these things are kind of replacement drugs. So, they're getting to the harm reduction model and again condoms in the middle school. You know, there's there's a Bob Newhart um episode. Uh the late great Bob New Hart. Uh company comes in for his office. She had a problem XY andZ. And he's like going to give her advice. It's like he's only going to need $5 going to be three minutes. She's like, "How can that be?" He's like, "His advice, cut to the chase." He's like, "Don't do that. Stop that." You know, this hurts. Then don't do it. Yeah. Yeah. But but it's like what we've done said in in because the we have nice people you know Marie literally named nice wander um you know people have with with kind of um softness in their heart and the grace of of wanting to help people doesn't mean they always do and it doesn't mean that that their ideas can translate into policy and and and people are funny things you know they sometimes go counter to the way that that the help would be there you know so that if we give some if you again if you have free condoms in middle school. You know, the message to the middle schoolers is, "Oh, we haven't been having sex. We should there's condoms. They're expecting us to have sex." You know, you know, every time they've improved the helmets on snowboarders and every time they put on better braces and and you know, better this and make things the sport safer, the snowboarders jump from higher heights. You know what we see now? We have a you know, people bicycling down mountains, whatever. You a lot of the times that we think we are reducing harm. What people actually want is the thrill and they they they go up to the edge of where the thrill is. If you draw the line here, you have kids, you know, you draw the line here, they they want to go there. And if you if the line were there, they want to go the thereer, you know, wherever it happens to be, they want to touch up against that because that is the essence of our discovery process. You know, as babies, we put everything in our mouth. We feel the world through our tongue and whatnot. And over time we have to experience the world a lot. I'm not I'm not recommending you know kind of freef fall for people. But I'll just put this out as a kind of question and you know over the same duration. Have we seen an alcohol epidemic? You know alcohol is freely available at a liquor store you know bartenders and wherever um and even amongst teenagers and so forth they can all find and get it. You know people alcohol is dangerous you know in excess and whatnot. to be a deadly and frankly alcohol withdrawal is more deadly than narcotic withdrawal but we don't have a government apparatus. Have we seen the same kind of expansion in alcoholism andor you know an opioid excuse me an alcohol epidemic when it's not something that the government has you know had some kind of cure for you know by by virtue of of of you know kindness and so forth. Well I mean alcohol deaths are about 178,000 per year. cigarette deaths are about 480,000 per year and we're just now below 100,000 opioid over or drug overdests per uh drug overdose deaths per year. So it's I mean it it's kind of like this is an issue I have with the people who are are very gung-ho just for legalization. You know, it's like well if we just legalize all drugs then you certainly have them under control and and regulations and things like that. And I don't necessarily believe with that believe that. Excuse me. Um, I'm sure you're familiar with the the iron law of prohibition, uh, which was, um, Dick Cohen wrote about that in the 1986, uh, National Review article. And then he actually went on to become the executive director of Normal, the National Organization for the Reform of Marijuana Laws. He was like the only sort of like uh, conservative Republican uh, executive director in the organization's history. But he argued, and a lot of people kind of glom on to this, that uh when a drug becomes prohibited, it becomes more powerful because it's easier to traffic a very small amount of fentinyl that can get 40,000 people high as opposed to a very large amount of morphine or opium, which is bulky and, you know, like it's very hard to hide in in, you know, like your clothes or your suitcases or whatever. And that's true, but there is just as much an iron law of legalization. And I think we're seeing that specifically in the realm of cannabis legalization. And we saw this in the realm of oxycodone legalization. The only reason we went from a 20 to a 40 to an 80 mgram tab of oxycontent was because Purdue Pharma was allowed to legally market these things. And the only way we've gotten to like 25 to 30% THC cannabis flour and 99% THC dabs is because of the legalization of the cannabis. these things are very very powerful because there's a whole lot of economic initiative behind that to make them powerful because people are always looking to push the edge. I think that's I think that's entirely true but I don't think that necessarily takes away the need for certain forms of of treatment or rehabilitation necessarily just because people are always trying to push the edge. I do think that that treatment of and and rehabilitation should be available to them even if they are pushing the boundaries. And the thing is like you're always going to have a lot of organizations and entrepreneurs who are seeking to profit off of and I hate to use the word again but exploit those individuals who are looking to push the boundaries. And 99% dab is not for like the like the user who's just like I want to relive my college days and smoke a joint. Those are for that, you know, it's like the 8020 rule, right? like um 80% of the sales of most intoxicants go to 20% of the most like sort of uh the highest the highest level users. And so I'm interested in in what you would then say if you know how how does one respond to uh a situation like this because I mean I think we've learned from the past couple of decades in the United States you can't necessarily just arrest your way out of this problem even in dealers and things like that. You don't arrest you don't arrest everybody. So uh have you been you choose to arrest then. Okay. Have you been to Japan? No, I was in South Korea in August though. That was fun. Well, does South Korea have maintenance narcotics? Gosh, what a great question. I don't know. But they um certainly alcohol is widely available. Cigarettes are widely available, but I think they have pretty harsh drug laws. I would say in Well, just to stay on topic, Addiction, Inc. is pretty much on the concept of opiates. Am I right? Hope you Yes. Fair enough. So, um, [clears throat] for my book, um, which I hope you will look at because I'd love to get your thoughts on it and maybe, uh, yes, you sent it to me. I started I I I was just dipping in before our conversation, so I'll go back and maybe you can get revenge on me. Um, you know, I I apologize if I, you know, give you, you know, kind of got you questions, but um, but I think you're good and and you're smart. Um, you can handle these things. Anyway, [laughter] um but uh you know for my book I was I was actually looking at Russia um which you know had we we had our kind of heroin moment from the Vietnam War um and it kind of got into our experience. I mean obviously heroin is predates this and you you bring up the interesting aspect of morphine clinics and you know morphine was there to treat opium and then heroin was there to treat morphine. Get back to my little lady swallow the fly. and um and methadone was there to treat heroin and in a sense buprenorphine is there to treat methadone. So you have is that five? I'm not good at numbers. Actually I think that is five. Um you know things in succession whatnot. Um but you know Russia had Afghanistan um their Afghanistan war uh I believe in the 70s and um they had a lot of you know there's a lot of dope in in Afghanistan. There's poppy fields and and um um heroin readily accessible. Um and they came up with a lot of addiction. So they had the same kind of ancillary problem. We had the, you know, the golden triangle. We had uh we we had troops in various times, Laos, Cambodia, and Vietnam. And uh there was, you know, not a lot to do there when you're off duty and and whatnot. People plus people were literally in pain here and there. And so they were doing heroin. And the the the image and actually the interesting um image from your book, I'm not going to show it here, but uh you have a Bill Sanders um the editorial cartoon. Yeah. Milwaukee Journal Sentinel in 1971. Uh he illustrated I have my book here. I can show it. [laughter] Fair enough. It's on uh if I can find it. Let's see what page is it on. It is on page 43. Um thank you. And uh so the idea is that uh you know we are going to be mainlining into the country. There's a needle and kind of these vicious devilish kind of uh fingernail monstrous hand. Yeah. Yeah. Is going to Vietnam. This is got this is we're going to uh you know there's the HL Mein said at one point uh dem theory of democracy is that people vote for what they want and they good need and they deserve to get it good and hard. I think the concept here is we got we got into the Vietnam War the Bard of Baltimore. I do love HL. Oh, it's great. And and so I think here um Mr. What is his name again? Um Bill Sanders. Bill Sanders. I think he has a little bit of um shenanoid towards the United States and we got into Vietnam. Well, here you're going to get this piece of Vietnam, you know, heroin injected into your body politic and bodies general so forth. Um, I don't think this actually happened. And I think a lot of the Oh, no, it didn't. Lot lot [laughter] the fright was there. I think I think Nixon a little bit got hoodwinkedked into the methodone concept because of the presumed numbers coming back from Vietnam. This was over and over. as a drum beat in the New York Times at the, you know, Erstwell, the Times, the Urswell Times or the Times, um, that this is going to some this is a ticking time bomb and and whatnot. Um, that that we're going to have all this massive influx of heroin addicts. And the fact of the matter is it it didn't happen. You know, there were heroin. It did happen for a variety of reasons. And one of the biggest reasons that it happened was because Jerome Jaffy, the head of the Special Action Office for Drug Abuse Prevention, or Seodap, just rolls off the tongue, um, instituted urine testing in in Vietnam. And you would not be allowed to leave the war zone if you tested positive for opiates. So, a whole lot of people stopped using heroin while they were still in Vietnam. And this was the biggest transformation in the field because if you think about it, prior to about 1970, 1971, the general medical consensus was that opioid addiction was a lifelong problem. You were never going to get off of it. This monkey was going to be on your back for the rest of your life. But what happened was as soon as he instituted urine testing in Vietnam with a brand new technology, the free radical essay technique or frat testing, which was allow which was this big bulky machine like you know the way like computers were in the 1960s, right? was a huge machine. But they brought two of them to Vietnam. One was in um Saigon, one was in um Long Bin, like the two main places that that service members were exiting the country. And a thousand service members are exiting every single day, right? There's about 300 service members who are there in like the peak of the war in 1970, 1971. And all of a sudden, you have to piss into a bottle and it's got to go through this little thing and it's going to show if you've used opioids in the past 72 hours. And if you have, you are not allowed to leave a war zone. There you go. And that's bad, right? People don't want to don't want to stay in Vietnam. So So what what they were able to do, what many of these soldiers were able to, and this is the difference between heroin use and heroin dependence/addiction. And Jaffy always knew this. He always knew that there was a difference. And he's like, if you can get the people who are simply using periodically to just simply stop once they come back to the United States, they're in a completely new environment. They're back home. They're with their family. They're with their friends. they probably will not continue heroin use. The people who do have an issue, the people who are addicted or dependent, who do test positive, yeah, they have to stay in detox in Vietnam, but when they come back to the US, there is services for them. And that's the biggest thing. There was no I mean, this is what comes from um gosh, why am I blanking? Washington University at St. Louis. Her name Lee Robbins. Oh, the woman. Thank you. Lee Robbins. She was this the report that she wrote after she followed 900 and some veterans returning from the US after this urine test and all this when she realized that heroin addiction or opioid addiction at large is not this lifelong chain that you have to wear around your neck and that was huge and but but no one had proven that before and it took an example like Vietnam to actually give people so the thing that that puzzles me is we have all these kind of dispositive evidence that this is not something you have to do forever but it But but if you read the press and if you recreate the New York Times of the times um in New York the times of the times yes well the uh [laughter] the times of the New York Times in New York um at the time of uh I can keep just I'll be here all day anyway um you will find exactly the opposite that this ticking time bomb uh image is is but that's the media firestorm. I mean that that well this has not been helpful you know I think I think this became a perfect storm. I'm not a conspiracy guy, but I am a conspiracy of interests guy. Uh, which is to say, the example I till I come up with a better one, the one I always use is I it's a hot day. I've got an ice cream cone and uh maybe it's soft serve and I'm walking down the street enjoying it and I'm like looking at something and all of a sudden hot it melts. It falls to the ground. Okay, the raccoons getting back to the raccoons or the flies, the insects, the ants. Um, I don't know. The little old lady's going to eat all of those, by the way. She's just coming for them. Exactly. all those animals, um, pigeons, whatever, they have no idea this going to happen. They're they're not conspiracy theorists about ice cream falling in this spot. It happens. And they once the ice cream's there, there's a whole apparatus and engineering going on. Who's going to get it the fastest? So, some pigeon's going to like try to whisk off at the whole thing. If it's a candy bar or whatever, and the answer, if it's if it's liquid, they're going to be in the cracks that anyway, there's a whole operation to deal with the fact that I dropped the ice cream cone. So nobody had the pre-ordained notion. There was no conspiracy about this happening. I didn't think I was what I was going to do. It just happened. But once something happens, once there's an attractive nuisance um or moral hazard, I guess you'd call it um there then then something happens beyond that. And so I think the the the inst the conspiracy of interest where a few different things happening confluently um in in our world, you know, Vietnam and this kind of concept that we had to get it good and hard for having violated, you know, whatever that the the Vietnam, you know, sovereignity, whatever we did, we had to be punished and and this whole drum beat about the the heroin thing is going to come bite us in the butt and the crime's going up and all this kind of thing. We need to have methanone maintenance because Vincent Dole had come up with this idea and Howard Sweet and nice you know Maria is and all kind of stuff. I think this was a bad idea applied and a wrong solution to a problem and I I you know you bring up Marie uh nice wanders work in Harlem. This guy Robert Beard are you familiar with him. I actually don't know the name contemporaneous. [clears throat] I have a Substack. I'll send it to you. I hadn't been either. I I found him researching for my book and uh it said Harlem doctor blah blah blah you know comes out against um you know the methadone clinics because he thinks it's going to bring more crime people are already addicted to stuff why add more you know narcotic into the mix all kind of stuff and I just assumed I don't know I assumed he was a local Harlem doctor but he wasn't he was an upper east side uh fill in the blank I think a diabetist he was endocrine guy and he was doing insulin and stuff and on his own. The guy's like a bleeping saint. I mean, he spent his nights going up to Harlem and with crime and all kind of stuff, driving the subway, whatever. Or maybe he drove his car, I don't know. But he he wound up in in East Harlem every night of the week and sometimes the weekends as well dealing with narcotic addicts and he he tried to get them unaddicted but he had group meetings and no drugs and he you know he might have I don't if he had anything palative or whatever but he his whole thing was to get them off drugs and he was just flumxed flabbergasted um etc etc that this was going to happen. he was, you know, yelling stop and and uh so I have a little piece on him does kind of a a payon to his his great work and totally ignored. Um but I don't think he was wrong. You know what happened was the the the rate the of heroin usage was highest in New York City amongst the whole country and New York City was the highest in Harlem Bedford the black neighborhoods not because they're black because they were poor they were they were had the highest rate when when it was like Italian and so forth because of the poorest area the poorest area in New York had the highest rate of heroin in the whole country because it's a port city um and that's that's where the stuff would land so the places where there were heroin problems through that era of classic control were Chicago uh New York LA in Fort Worth because on the you know the Texas border etc. And that's where the heroin was happening in so far as it was happening for those that duration and and the the rate was highest in the black population and over you know over the succeeding 20 years um the rate in Harlem was no longer higher than the rest of the country. So that sounds great but that's not because the Harlem rate went down. It's because everybody else went up to Harlem's rate. basically we Harlem was up here and all the tide everybody else wound up at Harlem's rate of narcotic usage and heroin use and so forth. So, you know, I kind of feel like that the, you know, we can we could talk about answers and solutions. Uh, but I feel as if this hasn't been it. You know, as if kind of the the harm reduction approach and that that you know, certainly, you know, we we know people who die from from opiates and that's tragic. Um I just don't know if we've applied the right answer to it given that say getting to Japan and and or Russia. Um that Japan does not didn't have an opioid epidemic. They didn't for the whole duration of our you know whatever you want to consider the 90s and zeros and whatnot. Uh they didn't have it you know and Russia didn't either. You know they Russia's got loads of problems. Don't get me wrong. I I wouldn't trade places with being in Russia. I might if I were Japanese to you know trade in Japan. I don't want to learn the language but if I whatever but but you know there are places that are there experiments being run right now they're called other countries that don't do this and frankly amongst our states we have other states that don't do it you know Wyoming does not do it um it's small place it's hard to you know get much data from that but Mary Jane Creek you know in one of these memorials to methadone and and self- congratulatory you know she she feels that that what we need is is universal mandatory maximum access to methadone um but of course that's not What the that was not the only thing that Seodap was promoting at the time when they were really in power from 1973 or 1971 to 1973. It all kind of fell apart in 1974 with everything else that fell apart in the Nixon administration with Watergate. But that this was not what necessarily Seab's emphasis was. It's by far the most controversial. It's by the it's the part that got them the most flak. It's the part that turned Jerry Jaffy into like a a sort of you know hated person in Washington. But methadone clinics that they were funding at the time were only about onethird of the clinics that they were funding otherwise. They were funding a lot of other programs, a lot of abstinence-based programs, detox programs, counseling, therapeutic communities, halfway houses, all of this other stuff. We hang this albatross around Seodap and Jerry Jaffy's neck saying, "Oh, you're Mr. Methadone and you're pushing this on the country and blah blah blah." But that's not what he was doing. He was um he was a big proponent of what he called multimodal treatment options. It was what the person wanted and could help them the most and that was simply to be made available to them at the time. Now remember, methadone is still very very new. In the 1970s, in 1970, I found a report that only 9,000 patients were on methodone maintenance in the United States and Canada combined. In 1971, that does increase because of SEOP support for methadone clinics. And that increases to about over uh there's over 72,000 people in federally funded addiction treatment care by the end of 1973. But only a third of those patients are me are methadone patients. It's not this overwhelming this is our only response and we've got to cut down crime and blah blah blah. He was funding a number of programs. And there was so much controversy about methadone. People hated it, especially in the black community because you're like I mean you're coming at the end of all of those racial uprisings, right? people who are saying like you after the assassination of Martin Luther King and all this other stuff, they're like, "We want better jobs. We want better housing. We want better schools. We don't want to live in these slums. Like, why don't you take care of these problems?" And when what they get are simply like therapeutic communities and methadone clinics, they're furious. They're like, "This is not the response that we were looking for." And methadone has been controversial from that point on. But, um, Jaffy very much dislikes that he is only remembered for his participation in the methadone clinic system. And that was why the first six times I talked to him on the phone when I was embarking on this project, he would he he he was like, "You're just here to tell me how awful methodone is and blah blah blah." He would make me cry. Like it was just awful. And finally, I won over his um his I I finally won his his trust when I was like, "No, I've read all of your papers at the Library of Congress. I do not think you're just Mr. Methadone. I think you actually instituted a program that was much more responsive to the wide variety of needs of a wide variety of people who use drugs." And then he finally started talking to me and he was giving me a lot of his papers that he did not donate to the Library of Congress that he kept in his basement. And that's how I found out a whole lot about the other stuff. But it is not um the Nixon administration wanted to get reelected in 1972. And in 1971, you have a perfect storm of three things, which is rising rates of heroin use in the United States, rising rates of crime in the United States. and the media freak out about addicted soldiers coming back from from Vietnam, the GI junkie phenomenon, which of course did not materialize. But the Nixon administration simply had to respond. So they do bring in Jaffy out of nowhere. He's he did not realize he was going to be the nation's first drugs. He just kept getting invited to Washington and then all of a sudden he's put out in front of Congress and the and the press and he's like, "Okay, we have a new drugar and you're in charge of $155 million, twothirds of the federal drug budget. You better open as many clinics as possible." the the biggest number you possibly can and you better bring down crime. I mean, he had a huge job in front of him and to his credit, he actually did it. Crime did decrease in 1972. It was a blip, went back up in the in the later 1970s, but he got it done by supporting as many options for treatment as possible, not just methadone. And um he was a big big big supporter of Lamb, Lalpha acetylmethad. He was a big supporter of Nalrexone. He was a supporter of all forms of addiction treatment that would get people to the point where they were no longer living lives of desperation. Right? And that's that I think is probably the most important thing I want people to take away from my book and from this conversation. Like it wasn't necessarily just trying to get Americans on maintenance and keep them on it forever. There was actually a really fullthroated support for a wide variety of treatment options. Um, and we've forgotten those and we've turned pretty much all of those actually into like money-making exploitative opportunities today. And that's that's bad in my opinion. That's where I come down on it. Yeah. No, I think you and I can agree on certain aspects of this. I I'm sure it's not my only I I don't I'm not saying I'm the inventor of this term, but I use the term methadone industrial complex. And um I agree. I think there is an MIC. [laughter] Yeah. And I I wonder and worry whether there's also a suboxone industrial complex in a sense as well. There is. There very much was. And it was actively created by Wreckit Benkezer Pharmaceuticals under the direction of Sean Ther I I don't know that precisely. So with methadone, you know, there's no there's no pharma company, you know, there is one. There's Malenrot makes the stuff, but it's all behind the scenes. It's all like the Wizard of Oz, you know, somebody behind the green curtain, all that kind of stuff. Nobody sees methadone. There's not commercial. There's no methadone commercial during the Super Bowl and you [clears throat] know I don't I don't even know if there's a brand of methadone. There used to be Dolphin or whatever but you know methadone is not there's no pharma push for methadone. There's no public push for methadone and yet methadone has expanded year by year by year and decade by decade. Um it may have been tempered a little bit by suboxone as an alternative mo you know modality you know which dstigmatized methadone and got rid of the methadone clinic you know kind of stink whatever nobody want wants to hang out there etc. Um but it's not the methodone industrial complex I think has much more to do with physicians and institutions that own those clinics and so they have a business model which is very interesting. I have an article I hope to get out in the [clears throat] city journal or someplace called the Starbucks of narcotics and [clears throat] it basically narcotics. This the puditive title is star the Starbucks of narcotics that Starbucks narcotics I mean I think good pun here I really like that and so uh you know Starbucks in my theory would would love not only to be able to dispense coffee but to get $50 every day for for for you know having you drink it especially in front of them or whatever drink your coffee and down it and we're going to get I don't know 45 bucks from the federal government or state or whatever for doing it. So, we're going to get a fee. Now, caffeine is addictive and people you could argue that oh, there's no reason. I mean, I I don't want to give a good idea to Starbucks, but um you know, they they would love it. You know, cigarette manufacturers would love to say, you know, we have this addictive product and you know, we're going to make sure we we dose people the right whatever. So, but but on the other hand, methadone does and I think it has much more to do with addiction and public health and you know if you look up uh you know the goo Google book uh engram you know the frequency of term usage addiction um we think of addictionologists and I'm sure they have their conventions every year but uh I I was surprised to see that you know it only came into being I think in the 1980s and it just grew as a term that's not like diabetist you know somebody like this do Dr. Robert Beard literally was a diabetes doctor and diabetes as a term has been around forever but if you follow kind of the medicalization addiction um addictionology um these are relatively recent conception not addiction per se but kind of the treatment around it is is a new formulation and and getting to the little lady in the fly I think the more things we do for this sometimes it we're not necessarily making the problem better and and I think we have to kind of detox uh from a lot of the you know a lot of the uh ideas that we just think are there. You know, if you ask a fish what's water, you know, he might not have any idea because he's like swimming in it all the time. He doesn't understand water being poured or water turning to ice cubes or whatever, you know. Yeah, that's just his world is water. And so I think we are in a world where we think this is what we do. We have where, you know, methadone opioid, excuse me, um medications for opioid use disorder. You know, we've created this stuff. the these are things that align with the addictionology, you know, college fund, you know, if you're an addictionologist, you want to get your kid through college, you know, this this has been very very good for the concept. All of a sudden, again, bartenders would love this, you know, if they could not only pour the drink, but get paid 40 bucks for having seen you, you know, and bill it to some third party that you're not aware of and and taxpayers not aware of. This is I think the real blackbox warning that should be out there that the methodone is a black box. It's it's right in plain sight but and and and and I I would put a slash with buprenorphine suboxone that these things are out there and there's been a huge expansion of it and it's been on the taxpayer dollar for the most part and um and they've been growing and their their method is essentially you know like thyroid replacement like you know they use their analogy themselves all the time it's like di like insulin for a diabetic. I do not think this is the case at all. You know, if you haul up uh, you know, in an Istanbul prison like that, Midnight Express, you know, some two guys with needles and one of them is a junkie with heroin, one of them is an insulin um diabetic and you take away their needles because they're both bad people, whatever something, you know, the the diabetic dies in two weeks. That's it. And the the heroin guy is like feeling awesome in in four weeks, not two weeks. And so you know this this concept where we are treating this but we don't treat addict you know sex addiction we don't have you know we don't have replacement um you know therapy for Tiger Woods you know to get see hookers we don't have gambling replacement you know where you go to Las Vegas only twice a week you know we don't do that for any of the other addictions I think you know people are addictable clearly um to various things um but I I think we have this idea that we are helping people by helping them and sometimes they they are only helped when they you know craft their own exit and it's a it's a it's a difficult thing. Well, I think you should talk to Sally Satell. She's a doctor here in DC. She actually works in a methodone clinic and her book is coming out. I have the galley. Um uh not a disease. Oh, there you go. Rethinking addiction in the heart of America's opio overdose crisis. She went to uh she spent a year in Ohio, Iron, Ohio, I believe. And uh this book's coming out and I think she would be someone who you could talk to specifically about that kind of stuff because she I think is very much a proponent of that idea as well. Well, sort sort of I mean we've exchanged emails and without without revealing any private s I've been in contact with her for like more than a decade. Um and Sally's great. Yeah. I've never met her and I will asked to be on the show and u at first she said yes but that you know my ideas about methadone are not hers and so she works for a methadone place. I don't know. You know, I'd love to hear what her concept in that book is. Maybe you could report back uh to me or whatever. I don't want to get you to tell. I'll give you a full report, but but I think there's there's, you know, an interesting aspect like I I've actually interviewed I don't know if you know Theodore Dal Rimple. Do you? Um his he's writes for City Journalist. His name is Anthony Daniels. Uh he he eventually dropped the um the pen name a few years ago. It's a great pen name though. Oh my god. Yeah. He I he told me how and why he picked it. There's another story. You got to watch the show. Um, but brilliant man. I I he totally, you know, you know, he's kind of my idol. Um, and he wrote a book in UK called Junk Medicine. And here it's called Romancing Opiates, which is a less less good title, but if you want to find the book and uh he covers a lot of things that I saw in real life, you know, IRL as the kids say. Anyway, um I want to give you the last last words and I've taken a lot of your time and I apologize. Um, but I very much Oh, this is fun. This is a joy. Thank you for having me. This is great. Um, and uh um I like I could come up with a a last question. Um, but but why should people find and read your book and and again, you did kind of some of the take-home messages, whatnot. Um, where do you think the best place for us to go with addiction treatment would go would be? Well, I hope people read my book. It would be great if you did. My publisher would be thrilled. But I think we we treat substances like methadone and buprenorphine and nrexone as sort of these fixed ideas that they just sort of arrived in our life and in our community and in our society and that's just how they've always been and that's just how it is. But there is a whole lot of action and historical building that goes into creating the systems in which these drugs now exist. And my book exposes and explains exactly where those systems came from. And I think it's kind of interesting the fact that Richard Nixon in 19 on June 17th, 1971 created this federal office, executive level federal office to oversee addiction treatment in the United States and it spiraled into something now 56 years later which is radically different. Is it better? Is it worse? I mean, I think that's up to the individual to say, but I do hope that if people are interested in understanding how we got to this point that they read my book and they figure it out. I've been um really having a lot of fun talking to uh medical schools. I've been talking to federal offices. I've been doing some consulting for people who are interested in understanding the mistakes and the successes that we've had in the past and how that can influence the future of addiction treatment. Now, going forward, I mean, I am not a licensed medical practitioner. I don't know what's going to help, but I know a lot of people who have really benefited from that. I know a lot of people who are on it for a while and they've tapered off and they're living great lives. And I know a lot of people who are dead and I don't know them anymore because they're dead. But I do think that I I I I'm just on the side of the individual who's struggling, who needs help. And I'm a big fan of offering them a suite of options with sustainable and supportive people to allow that person to achieve whatever sustainable and supportive sense of sobriety and remission and recovery looks like. I am not here to grind an axe. I really just don't want my friends to die anymore. That's my That's my platform. It's a hill I'll die on to not see my friends die. That's it. Well, that's awesome. I'm I'm the one always grinding axes. I keep I keep a whole bunch you can't see them, but I keep a whole bunch sharp behind me. [laughter] You're a wood chopper. I get it. My wife here. My wife thinks grievance is my chew toy. And actually, it's not quite true. Um I I kind of enjoy the day most days, but there are things that I think uh need to be called out here and there and so that's somehow fallen to me and I'm I'm currently now an old um so um at the latter part of my career I kind of you know say what I need to say. Um anyway, thank you so much Emily. I it's been a pleasure. I hope I can have you on again um and uh discuss any slashall of these ideas and topics and it's been a complete pleasure and joy. It's been such a pleasure. Thank you so much for having me. I really enjoyed it.